@techreport{oai:niigata-u.repo.nii.ac.jp:00033247, author = {田邊, 裕治}, month = {May}, note = {The purpose of this study is to develop the method for the determination of mechanical properties of the degenerated articular cartilage. Previous studies found differences in permeability between normal articular cartilage (hyaline cartilage), and OA cartilage (fibrocartilage), and therefore different time-dependent water content after indentation testing was expected between these two cartilages. First, this study deals with the two aspects of the detailed relations between recovery of absorbance and degeneration of human cartilage, that is,1) relation between the degeneration of human articular cartilage and pattern of absorbance with respect to time after removal of indentation load, 2) relation between the degeneration of human articular cartilage graded by Mankin Score and variation of absorbance with time after removal indentation load. Second, this study discusses the decreases of absorbance for cartilages and koya-tofu during compression. The recoveries of absorbance after indentation were classified into 3 patterns. Initial decrease and the subsequent increase of absorbance (pattern 1), immediate increase of absorbance after removal of indentation load (pattern 2), and no recovery of absorbance (pattern 3) were observed. In the most of specimens graded as "normal", the recovery pattern of absorbance was "pattern 1". In the specimens of "pattern 1", the Mankin Score was able to be related to the time when absorbance had the minimum value. In the specimen of "pattern 2", the mean ±S.D. of Mankin Score was 3.6±2.0. Cartilages showed the increase of absorbance during compression, while koya-tofu showed the decrease of absorbance during compression., 平成16年度~平成18年度科学研究費補助金(基盤研究(C))研究成果報告書(課題番号:16560063)}, title = {変形性関節症診断のための近赤外線水分計による関節軟骨の含水量測定法の開発}, year = {2007} }