{"created":"2021-03-01T06:38:15.917933+00:00","id":32021,"links":{},"metadata":{"_buckets":{"deposit":"cf462487-0b3d-4e89-8519-8b7c05c55114"},"_deposit":{"id":"32021","owners":[],"pid":{"revision_id":0,"type":"depid","value":"32021"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00032021","sets":["453:455","471:561:562"]},"item_6_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"低体温療法を施行した新生児仮死児の甲状腺機能"}]},"item_6_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-09-20","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{}]}]},"item_6_date_granted_51":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2018-09-20"}]},"item_6_degree_grantor_49":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"新潟大学"}]}]},"item_6_degree_name_48":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）"}]},"item_6_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Thyroid function of asphyxiated newborns who received hypothermia therapy and its relation to neurological outcome are not well described. Methods: This is a prospective study measuring thyroid function of 12 asphyxiated newborns who received hypothermia therapy. We measured serum thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) levels on admission, 24, 72, and 96 hours after birth, and at discharge (17-54 days). Twelve newborns were divided into two groups based on the presence of brain injury on head magnetic resonance imaging findings (six in the abnormal imaging group and six in the normal imaging group) and their thyroid functions were compared between the twogroups. Results: Serum TSH levels were within a normal range. Serum FT3 and FT4 levels remained low at 24, 72, and 96 hours after birth, and returned to a normal range at discharge. There was no significant difference in serum TSH levels between the two groups. However, serum FT4 levels at 72 hours after birth, and serum FT3 and FT4 levels at 96 hours after birth were significantly lower in the abnormal imaging group than those in the normal imaging group (p=0.03, p=0.02, and p=0.01, respectively). Conclusion: These results suggest that asphyxiated newborns have transient low thyroid hormone levels at 24-96 hours after birth. Serum FT3 and FT4 levels between 72 and 96 hours after birth may predict brain injury of asphyxiated newborns.","subitem_description_type":"Abstract"}]},"item_6_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"学位の種類: 博士（医学）. 報告番号: 甲第4495号. 学位記番号: 新大院博（医）甲第832号. 学位授与年月日: 平成30年9月20日","subitem_description_type":"Other"},{"subitem_description":"Pediatrics International. 2018, 60(5), 433-437. First published: 20 February 2018.","subitem_description_type":"Other"}]},"item_6_description_53":{"attribute_name":"学位記番号","attribute_value_mlt":[{"subitem_description":"新大院博（医）甲第832号","subitem_description_type":"Other"}]},"item_6_dissertation_number_52":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"13101甲第4495号"}]},"item_6_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"175076","nameIdentifierScheme":"WEKO"}],"names":[{"name":"小林, 玲"}]}]},"item_6_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟大学"}]},"item_6_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1111/ped.13534","subitem_relation_type_select":"DOI"}}]},"item_6_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"ETD"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kobayashi, Akira"}],"nameIdentifiers":[{"nameIdentifier":"175075","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-10"}],"displaytype":"detail","filename":"h30nmk832.pdf","filesize":[{"value":"442.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://niigata-u.repo.nii.ac.jp/record/32021/files/h30nmk832.pdf"},"version_id":"924902a8-5a2b-4acb-9973-52fd8af85737"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-10"}],"displaytype":"detail","filename":"h30nmk832_a.pdf","filesize":[{"value":"446.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"要旨","url":"https://niigata-u.repo.nii.ac.jp/record/32021/files/h30nmk832_a.pdf"},"version_id":"cc34cc3d-8041-4f25-9dd9-24d5baeec9c9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"Thyroid Function of Asphyxiated Newborns who Received Hypothermia Therapy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Thyroid Function of Asphyxiated Newborns who Received Hypothermia Therapy"},{"subitem_title":"Thyroid Function of Asphyxiated Newborns who Received Hypothermia Therapy","subitem_title_language":"en"}]},"item_type_id":"6","owner":"1","path":["455","562"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-05-21"},"publish_date":"2019-05-21","publish_status":"0","recid":"32021","relation_version_is_last":true,"title":["Thyroid Function of Asphyxiated Newborns who Received Hypothermia Therapy"],"weko_creator_id":"1","weko_shared_id":2},"updated":"2022-12-15T04:02:21.923876+00:00"}