@article{oai:niigata-u.repo.nii.ac.jp:00028575,
 author = {Sekiya, Masaru and Ebata, Kiyokazu and Yamamura, Osamu},
 issue = {1},
 journal = {新潟大学保健学雑誌, 新潟大学保健学雑誌},
 month = {Mar},
 note = {A spontaneous echo contras（t SEC）is often seen in intravenous ultrasound examinations of the lower extremities. The SEC shows a thrombus preparatory state and implies the possibility of a symptom of an embolic disease. Although the SEC is reproducible in vitro using human blood, it is difficult to keep its condition constant. The generation of artificial SECs may contribute to the diagnostic decision-making process and assessment of the treatment effects. In this study, we attempted to produce artificial SECs using various types of solutions other than human blood. Several types of solutions, such as tomato juice, canned sugar‐free coffee, and instant café au lait were used for the experiment. We observed ultrasound images of these solutions flowing through two types of tubes（5 mm and 8 mm in diameter）and compared these with clinical SEC images. As a result, we found that a triple concentration solution of instant café au lait could be used instead of human blood regardless of the diameter of the tubes. Moreover, the SEC was able to be reproduced regardless of the flow velocity of the solution.},
 pages = {33--38},
 title = {Generation of spontaneous echo contrast using non-human blood},
 volume = {11},
 year = {2014}
}