{"created":"2021-03-01T06:31:22.389756+00:00","id":25854,"links":{},"metadata":{"_buckets":{"deposit":"05351c85-b50d-4afc-bd61-ca4f50f0e8f1"},"_deposit":{"id":"25854","owners":[],"pid":{"revision_id":0,"type":"depid","value":"25854"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00025854","sets":["432:1291:1292:1321","453:456"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Multiple primary oral carcinomas assumed to have developed from an extensive precancerous lesion. Report of a case"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"62","bibliographicPageStart":"59","bibliographicVolumeNumber":"28","bibliographic_titles":[{"bibliographic_title":"新潟歯学会雑誌"},{"bibliographic_title":"新潟歯学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Multiple primary carcinomas developed from an extensive precancerous lesion is reported. The patient was a 70-year-old woman who complained of burning sensation of the buccal mucosa. A large white lesion was extending from the right buccal mucosa to the lateral border of the tongue. Clinical diagnosis was lichen planus, but histologically, the lesion was diagnosed as epithelial dysplasia. The lesion gradually spread laterally and became erosive with time. Sixteen months later, a tumorous lesion developed in the gingiva of the mandible was diagnosed as squamous cell carcinoma (T2N｡M｡) by biopsy. It was treated by mandibulectomy and dissection of the submandibular area. Nine months later, the second carcinoma (T2NoMo) was noted in the floor of the mouth. It was removed surgically, but two years later, the third carcinoma (T1N2bMo) with lymph node metastasis developed in the posterior tongue. It was treated by local resection and radical neck dissection. The patient died of multiple metastases. Because all carcinomas were squamous cell carcinomas, they were assumed to have developed multicentrically from the lesion showing epithelial dysplasia.","subitem_description_type":"Abstract"},{"subitem_description":"広範な前癌病変から口腔粘膜癌が多発したと思われる症例を経験したので報告する｡症例は70才、女性｡頬粘膜にしみる感じがあるとの主訴で当科初診した｡初診時に右側頬粘膜から舌側縁にかけて広範な白色病変を認めた｡臨床診断は京平苔癬であったが、病理診断は上皮異形成であった｡その病変は時間の経過とともにその範囲が拡大し、表面性状も赤色に変化した。6ヶ月後、病変の範囲内の下顎歯肉に、生検にて扁平上皮癌と診断された1次癌(T2N｡M｡)が出現し、下顎骨区域切除術、顎下部廓清術を施行した｡その9ヶ月後、2次癌(T2N｡M｡)が右側口底に認められ、腫瘍切除術を施行した。その2年後、右側舌背後方に3次癌が出現し、頚部リンパ節転移も認められ(T1N2bM。)、腫蕩切除術と全頚部廓清術を施行した。その1年半後、癌は数カ所に転移し、その制御が困難となり、患者は死亡した｡本例では、いずれの癌も扁平上皮癌であったため、広範な前癌病変から多中心性に癌が発生したと推測された。","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"152583","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yoshizawa, Michiko"}]},{"nameIdentifiers":[{"nameIdentifier":"152584","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nomura, Tsutomu"}]},{"nameIdentifiers":[{"nameIdentifier":"152585","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kohno, Masaki"}]},{"nameIdentifiers":[{"nameIdentifier":"152586","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Shingaki, Susumu"}]},{"nameIdentifiers":[{"nameIdentifier":"152587","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakajima, Tamio"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟歯学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN0018300X","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03850153","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"芳澤, 享子"}],"nameIdentifiers":[{"nameIdentifier":"152578","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野村, 務"}],"nameIdentifiers":[{"nameIdentifier":"152579","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河野, 正己"}],"nameIdentifiers":[{"nameIdentifier":"152580","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"新垣, 晋"}],"nameIdentifiers":[{"nameIdentifier":"152581","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島, 民雄"}],"nameIdentifiers":[{"nameIdentifier":"152582","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-19"}],"displaytype":"detail","filename":"NS_28(2)_59-62.pdf","filesize":[{"value":"2.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"NS_28(2)_59-62.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/25854/files/NS_28(2)_59-62.pdf"},"version_id":"cfe74378-685a-4ec7-ab0c-ab6a7b3ab8a7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"multiple primary carcinomas","subitem_subject_scheme":"Other"},{"subitem_subject":"多発癌","subitem_subject_scheme":"Other"},{"subitem_subject":"squamous cell carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"扁平上皮癌","subitem_subject_scheme":"Other"},{"subitem_subject":"precancerous lesion","subitem_subject_scheme":"Other"},{"subitem_subject":"前癌病変","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"広範な前癌病変から多中心性に発生したと思われる口腔癌の1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"広範な前癌病変から多中心性に発生したと思われる口腔癌の1例"},{"subitem_title":"広範な前癌病変から多中心性に発生したと思われる口腔癌の1例","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1321"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-08-22"},"publish_date":"2013-08-22","publish_status":"0","recid":"25854","relation_version_is_last":true,"title":["広範な前癌病変から多中心性に発生したと思われる口腔癌の1例"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:55:53.034461+00:00"}