@article{oai:niigata-u.repo.nii.ac.jp:00025747,
 author = {加藤, 幸生 and 宮, 琳 and 泉, 直也 and 加納, 浩之 and 高田, 真仁 and 小林, 正治 and 新垣, 晋 and 齊藤, 力},
 issue = {2},
 journal = {新潟歯学会雑誌, 新潟歯学会雑誌},
 month = {Dec},
 note = {A case of report is presented in which mandibular trismus was the important symptom of tetanus. A 66-year-Old woman was referred to our hospital for evaluation and treatment of trismus and stiffness of the neck muscles. There were no laboratory abnormalities. She was diagnosed as tetanus and treated in internal medicine of neurology. A dose of 2.4 million U penicillin-G was administered on the day of admission. Furthermore, 3000 U of antitetanic human immunoglobulin and 0.5 ml of tetanus toxoid were administered intravenously for 2 days. She was discharged on the 32th day uneventfully. However generalized spasms had developed, a critical condition was avoided by initiating proper treatment for tetanus. Although tetanus has become a rare disease, it should be included in the differential diagnosis when treating the patient who has trismus. Severe trismus associated with clenching is an important sign for tetanus. The early recognition and treatment of tetanus would seem essential to avoid morbidity and mortality associated with the disease., 開口障害を主訴として受診した、破傷風患者の1例を報告した｡患者は66歳の女性で、紹介により口腔外科を受診した｡頚部の筋強直などが認められたが、血液検査では異常は指摘されなかった｡現症および臨床経過より破傷風の可能性が高いと診断し、神経内科に紹介し同日転科となった｡入院当日より、ペニシリンG (240万単位/日)の連日投与を開始｡また抗破傷風人免疫グロブリン(3000単位/日)と破傷風トキソイド(0.5ml/日)を2日間投与した｡入院時よりすでに全身性の痙攣が出現していたが、幸いにも治療が秦功し、入院から32日後に軽快退院となった｡現在では破傷風は稀な疾患となったが、開口障害を生じうる他の疾患と誤診され、治療をする可能性もある｡くいしばりをともなう重度の開口障害などは、破傷風と他の疾患を鑑別する際の重要な症状となる｡歯科･口腔外科領域においても破傷風の病態について充分理解し、早期診断、早期治療に努めることが重要である｡},
 pages = {57--60},
 title = {口腔外科受診により発見された破傷風の1例},
 volume = {31},
 year = {2001}
}