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the present study, we have investigated the relationship between oral mucosa humidity and salivary flow rate, which affect the oral wetness firstly, and then examined the time-dependent changes in the moisturizing effects of the two different types of moisturizers which are used in clinical practice, in order to higher the oral wetness. Subjects were 20 healthy adults selected from both sexes who have no history of disease associated with dry mouth symptoms. First, oral mucosal humidity (%) under a resting condition was determined by using an oral moisture checker (Mucus^). Total amount of saliva (g) was determined ordinary by using a cotton method. No significant correlation between mucosal humidity and salivary flow rate was observed. Since mucosal humidity and salivary flow rate have different implications with each other, it is difficult to evaluate by measuring only mucosal humidity in order to determine the oral wetness.Then, time-dependent changes in oral wetness with applying two moisturizers (Honey Wet^ and Members mouthwash fluid^) were investigated. Stimulation with Honey Wet^ caused sharp increase in salivary volume which returned to resting level within 20 min after the stimulation; whereas the stimulation with Members mouthwash fluid^ resulted in a mild increase in comparison to Honey Wet^ , however, the salivary volume was significantly greater than those of resting and tap water stimulation, even 30 min after the stimulation. Considering the application in clinical practice, Honey Wet^ is recommended when the marked dry mouth was observed and/or immediately before meal, where the increase in salivary flow is desired in order to swallow foods easily; on the other hand, Members mouthwash fluid^ is recommended when symptoms of dry mouth are observed because of habitual mouth-breathing and long-lasting moisturizing effects are desired.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"\u8457\u8005\u5225\u540d","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"150083","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tamura, Yutaka"}]},{"nameIdentifiers":[{"nameIdentifier":"150084","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sakurai, Akira"}]},{"nameIdentifiers":[{"nameIdentifier":"150085","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yamamura, 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