{"created":"2021-03-01T06:30:52.067867+00:00","id":25403,"links":{},"metadata":{"_buckets":{"deposit":"182261ff-86c0-4b02-a1df-6c61548c8ffa"},"_deposit":{"id":"25403","owners":[],"pid":{"revision_id":0,"type":"depid","value":"25403"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00025403","sets":["432:1291:1292:1294","453:456"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"頭頸部癌の切除不能頸部リンパ節転移巣に対する温熱化学放射線療法 : 治療成績および予後因子について"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"36","bibliographicPageStart":"27","bibliographicVolumeNumber":"42","bibliographic_titles":[{"bibliographic_title":"新潟歯学会雑誌"},{"bibliographic_title":"新潟歯学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of this study is to investigate the important prognostic factors in order to improve the outcomes of thermochemoradiotherapy (TCR) for patients with head and neck cancers. Materials and methods: We performed TCR for 15 patients with 20 inoperable metastatic cervical lymph nodes. Hyperthermia was done 8.8 sessions on an average by microwave or radiofrequency heating system. Chemotherapy consisted of a combination of cisplatin and pepleomycin or 5-fluorouracil. Additionally, external irradiation was used as radiotherapy. Results: Among the 20 lesions, 8 (40.0%) had a complete response, 8 (40.0%) had a partial response, and 4 (20.0%) had no change. The total response rate was 80.0%. The overall cumulative local control rate (CLCR) at 5 years was 64.2%. As to the dose of irradiation, the CLCR was 80.2% at 5 years in patients given 50 Gy or more and 0% at 3 months in those given 30 Gy or less. Statistical analysis showed that the total radiation dose was significantly related to the CLCR (P<0.05). There were no significant correlations between the CLCR and any other treatmentrelated factors (hyperthermia system, number of hyperthermia sessions, total dose of cisplatin, drugs given with cisplatin) or tumor-related factors (recurrence or not, tumor size, WHO classification, mode of invasion). Conclusion: TCR given 50 Gy or more is an effective strategy for inoperable metastatic cervical lymph nodes in patients with head and neck cancer.","subitem_description_type":"Abstract"},{"subitem_description":"この研究の目的は頭頸部癌患者対する温熱化学放射線療法の成績向上のための重要な予後因子について検討することである。対象および方法：15名の切除不能頸部リンパ節転移20病巣に対して温熱化学放射線療法を行なった。温熱療法はマイクロ波またはRF波加温装置を用いて平均で8.8回実施した。化学療法はシスプラチンにペプレオマイシンまたは5Fuを併用し，さらに，外照射を加えた。結果：20 病巣中８例（40％）は著効，８例（40％）は有効であったが，残りの４例（20％）では変化がなかった。奏効率は80％であった。全例の５年累積病巣制御率は64.2％を示し，放射線量別では，50Gy以上の照射例では５年病巣制御率は80.2％に対し，30Gy 以下の照射例では３か月で０％であった。統計学的解析により放射線療法の総線量は累積病巣制御率との間に有意差が認められた（P＜0.05）。他の治療に関する因子（温熱療法の方法，回数，シスプラチン投与量，併用薬）および腫瘍に関する因子（再発巣か否か，腫瘍の大きさ，WHO分類，癌浸潤様式）では，病巣制御との間に有意差は認められなかった｡結論：50Gy 以上を併用した温熱化学放射線療法は頭頸部癌の切除不能な頸部リンパ節転移巣に対する効果的な治療方法であることが示された。","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"149732","nameIdentifierScheme":"WEKO"}],"names":[{"name":"星名, 秀行"}]},{"nameIdentifiers":[{"nameIdentifier":"149733","nameIdentifierScheme":"WEKO"}],"names":[{"name":"永田, 昌毅"}]},{"nameIdentifiers":[{"nameIdentifier":"149734","nameIdentifierScheme":"WEKO"}],"names":[{"name":"高木, 律男"}]},{"nameIdentifiers":[{"nameIdentifier":"149735","nameIdentifierScheme":"WEKO"}],"names":[{"name":"藤田, 一"}]},{"nameIdentifiers":[{"nameIdentifier":"149736","nameIdentifierScheme":"WEKO"}],"names":[{"name":"安島, 久雄"}]},{"nameIdentifiers":[{"nameIdentifier":"149737","nameIdentifierScheme":"WEKO"}],"names":[{"name":"児玉, 泰光"}]},{"nameIdentifiers":[{"nameIdentifier":"149738","nameIdentifierScheme":"WEKO"}],"names":[{"name":"池田, 順行"}]},{"nameIdentifiers":[{"nameIdentifier":"149739","nameIdentifierScheme":"WEKO"}],"names":[{"name":"齋藤, 正直"}]},{"nameIdentifiers":[{"nameIdentifier":"149740","nameIdentifierScheme":"WEKO"}],"names":[{"name":"小林, 孝憲"}]},{"nameIdentifiers":[{"nameIdentifier":"149741","nameIdentifierScheme":"WEKO"}],"names":[{"name":"嵐山, 貴徳"}]},{"nameIdentifiers":[{"nameIdentifier":"149742","nameIdentifierScheme":"WEKO"}],"names":[{"name":"小山, 貴寛"}]},{"nameIdentifiers":[{"nameIdentifier":"149743","nameIdentifierScheme":"WEKO"}],"names":[{"name":"小玉, 直樹"}]},{"nameIdentifiers":[{"nameIdentifier":"149744","nameIdentifierScheme":"WEKO"}],"names":[{"name":"勝見, 祐二"}]},{"nameIdentifiers":[{"nameIdentifier":"149745","nameIdentifierScheme":"WEKO"}],"names":[{"name":"小川, 信"}]},{"nameIdentifiers":[{"nameIdentifier":"149746","nameIdentifierScheme":"WEKO"}],"names":[{"name":"山田, 一穂"}]},{"nameIdentifiers":[{"nameIdentifier":"149747","nameIdentifierScheme":"WEKO"}],"names":[{"name":"魚島, 勝美"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟歯学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN0018300X","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03850153","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hoshina, Hideyuki"}],"nameIdentifiers":[{"nameIdentifier":"149716","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagata, Masaki"}],"nameIdentifiers":[{"nameIdentifier":"149717","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takagi, Ritsuo"}],"nameIdentifiers":[{"nameIdentifier":"149718","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujita, Hajime"}],"nameIdentifiers":[{"nameIdentifier":"149719","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ajima, Hisao"}],"nameIdentifiers":[{"nameIdentifier":"149720","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kodama, Yasumitsu"}],"nameIdentifiers":[{"nameIdentifier":"149721","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikeda, Nobuyuki"}],"nameIdentifiers":[{"nameIdentifier":"149722","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saitoh, Masanao"}],"nameIdentifiers":[{"nameIdentifier":"149723","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kobayashi, Takanori"}],"nameIdentifiers":[{"nameIdentifier":"149724","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Arashiyama, Takanori"}],"nameIdentifiers":[{"nameIdentifier":"149725","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koyama, Takahiro"}],"nameIdentifiers":[{"nameIdentifier":"149726","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kodama, Naoki"}],"nameIdentifiers":[{"nameIdentifier":"149727","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Katsumi, Yuji"}],"nameIdentifiers":[{"nameIdentifier":"149728","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogawa, Shin"}],"nameIdentifiers":[{"nameIdentifier":"149729","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Kazuho"}],"nameIdentifiers":[{"nameIdentifier":"149730","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Uoshima, Katsumi"}],"nameIdentifiers":[{"nameIdentifier":"149731","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-19"}],"displaytype":"detail","filename":"NS_42(1)_27-36.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"NS_42(1)_27-36.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/25403/files/NS_42(1)_27-36.pdf"},"version_id":"0e9cd17c-4762-41e2-aaa6-e695c1aa35b6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hyperthermia","subitem_subject_scheme":"Other"},{"subitem_subject":"thermochemoradiotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"head and neck cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"metastatic cervical lymph node","subitem_subject_scheme":"Other"},{"subitem_subject":"prognostic variable","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Thermochemoradiotherapy for inoperable metastatic cervical lymph nodes of patients with head and neck cancer: Analysis of clinical outcomes and prognostic variables","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Thermochemoradiotherapy for inoperable metastatic cervical lymph nodes of patients with head and neck cancer: Analysis of clinical outcomes and prognostic variables"},{"subitem_title":"Thermochemoradiotherapy for inoperable metastatic cervical lymph nodes of patients with head and neck cancer: Analysis of clinical outcomes and prognostic variables","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1294"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-07-26"},"publish_date":"2017-07-26","publish_status":"0","recid":"25403","relation_version_is_last":true,"title":["Thermochemoradiotherapy for inoperable metastatic cervical lymph nodes of patients with head and neck cancer: Analysis of clinical outcomes and prognostic variables"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:55:19.590207+00:00"}