@article{oai:niigata-u.repo.nii.ac.jp:00024705, author = {芝田, 充男 and 庭山, 清八郎 and 落合, 宏 and 岩瀬, 勇雄 and 内山, 豊蔵 and 元田, 昭策 and 佐藤, 征也}, issue = {6}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jun}, note = {The degree of antigenic variation of the isolated influenza viruses and its relation to the characteristics of influenza epidemics were studied during 1978 and 1985. Influenza A (H1N1) epidemics moderate in scale were experienced in the five winters (1978~1981and 1984). A (H3N2) virus was not superseded by the newly appeared A (H1N1) virus in 1978, resulting in A (H3N2) epidemics small in scale in 1978 and 1980, and furthermore moderate in scale in 1983 and 1985. B epidemics were also experienced in 1980 at which A (H1N1and H3N2) epidemics were reported. Thereafter, B epidemics moderate in scale were experienced in 1982 and 1985. Characteristically, although the number of isolates was small, B viruses were always isolated in the pretracted epidemic season, showing an accurate indication of predictions for occuring of B epidemic in the next epidemic season. The isolates of either influenza virus types (or subtypes) successively showed more intense antigenic drift toward the recent epidemics. As a result, influenza epidemics were ceaselessly experienced in the order : A (H1N1), B and A (H3N2) epidemics, in three year cycles, reflecting the decrease of antibodies to each influenza virus type (or subtype) and the high frequency of isolates with intense antigenic drift.}, pages = {344--356}, title = {1978年から1985年までの新潟県におけるインフルエンザについて : 分離ウイルスを中心とした抗原分析}, volume = {100}, year = {1986} }