@article{oai:niigata-u.repo.nii.ac.jp:00024673,
 author = {風間, 嘉晶 and 丹羽, 正弘 and 近藤, 信一 and 高橋, 薫 and 櫻川, 信男 and 宮川, 照夫 and 新井, 弘之},
 issue = {7},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Jul},
 note = {Protein C, a vitamin K-dependent serine protease zymogen, is one of serine proteases which works in the regulatory systems of blood coagulation. Activation of protein C by thrombin is markedly enhanced by the thrombomodulin in the endothelial cell. Activated protein C exerts an anticoagulant by inhibiting F. Va and F. VIIIa selectively. Protein C levels were measured by the amidolytic activity of the activated protein C against the chromogenic substrate (S-2266) in the patients with the cerebrovascular diseases, the patients with liver cirrhosis, and the patients receiving warfarin therapy. Protein C levels in the patients with cerebrovascular diseases were normal, whereas its ievels in the patients with liver cirrhosis and patients receiving warfarin therapy were significantly low, 33.2±23% and 65±21%, respectively.},
 pages = {398--401},
 title = {肝硬変および脳血管障害時でのprotein Cの変動},
 volume = {100},
 year = {1986}
}