{"created":"2021-03-01T06:29:58.801806+00:00","id":24599,"links":{},"metadata":{"_buckets":{"deposit":"b3929f27-63d3-4786-b6a8-4363730c948f"},"_deposit":{"id":"24599","owners":[],"pid":{"revision_id":0,"type":"depid","value":"24599"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00024599","sets":["453:456","471:537:538:1242"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Drug-induced Hematologic Disorders (Present Status of Drug Allergy)"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1986-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"516","bibliographicPageStart":"506","bibliographicVolumeNumber":"100","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It is widely known that the hematological manifestations associated with exposure to drugs are dramatic and often fatal. In this paper, drug-induced hematological diseases, which are divided into 6 groups including red blood cell disorders, white blood cell disorders, platelet disorders, aplastic anemia, coagulation disorders, and therapy related leukemia, are reviewed. For each group, We presented a typical case and summerized not only the current state of knowledge about the pathogenetic mechanism but also the diagnostic procedures which are capable of identifying the causal drug. Since drugs can induce almost all hematological disorders, it must be emphasized that the hematologists should always doubt that the laboratory datas or the clinical manifestations might be induced from drugs when they encounter the patients with hematological diseases. And, when the signs of drug-induced hematological diseases are clinically apparent, the suspected causal drug should be stopped as soon as possible. Although it is difficult to identify the causal drug using the present technical procedures in vitro, the patient's plasma or serum at onset should be preserved, anticipating further developement of diagnostic procedures.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"146854","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Fuse, Ichiro"}]},{"nameIdentifiers":[{"nameIdentifier":"146855","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Takahashi, Masuhiro"}]},{"nameIdentifiers":[{"nameIdentifier":"146856","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Takizawa, Shinichiro"}]},{"nameIdentifiers":[{"nameIdentifier":"146857","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Soga, Norishige"}]},{"nameIdentifiers":[{"nameIdentifier":"146858","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Takeshige, Tomio"}]},{"nameIdentifiers":[{"nameIdentifier":"146859","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hattori, Akira"}]},{"nameIdentifiers":[{"nameIdentifier":"146860","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Shibata, Akira"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"布施, 一郎"}],"nameIdentifiers":[{"nameIdentifier":"146847","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高橋, 益広"}],"nameIdentifiers":[{"nameIdentifier":"146848","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"滝沢, 慎一郎"}],"nameIdentifiers":[{"nameIdentifier":"146849","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"曽我, 謙臣"}],"nameIdentifiers":[{"nameIdentifier":"146850","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"竹重, 富雄"}],"nameIdentifiers":[{"nameIdentifier":"146851","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"服部, 晃"}],"nameIdentifiers":[{"nameIdentifier":"146852","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柴田, 昭"}],"nameIdentifiers":[{"nameIdentifier":"146853","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-19"}],"displaytype":"detail","filename":"100(9)_506-516.pdf","filesize":[{"value":"878.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"100(9)_506-516.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/24599/files/100(9)_506-516.pdf"},"version_id":"2e4097c4-ffb1-46d9-8a29-d468fe60df56"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"drug","subitem_subject_scheme":"Other"},{"subitem_subject":"blood disorders","subitem_subject_scheme":"Other"},{"subitem_subject":"薬剤性血液障害","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"4) 薬剤による血液障害(シンポジウム 「薬剤アレルギーの現状」, 第415回新潟医学会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"4) 薬剤による血液障害(シンポジウム 「薬剤アレルギーの現状」, 第415回新潟医学会)"},{"subitem_title":"4) 薬剤による血液障害(シンポジウム 「薬剤アレルギーの現状」, 第415回新潟医学会)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1242"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-12-07"},"publish_date":"2015-12-07","publish_status":"0","recid":"24599","relation_version_is_last":true,"title":["4) 薬剤による血液障害(シンポジウム 「薬剤アレルギーの現状」, 第415回新潟医学会)"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:54:43.487253+00:00"}