{"_buckets": {"deposit": "ecb900cc-b2c2-49db-ba35-2da84e72b70f"}, "_deposit": {"id": "24551", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "24551"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00024551", "sets": ["456", "1241"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Characterization of human peripheral lymphocytes stained by anti-myelin-associated glycoprotein"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1986-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "601", "bibliographicPageStart": "585", "bibliographicVolumeNumber": "100", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We found that the same antigenic determinant as myelin-associated glycoprotein （MAG) of human central nervous system （CNS）exists on the cell surface of mononuclear cells in human peripheral blood, which was counted to 8.5±2.7% of mononuclear cells from 41 healthy individuals when stained by anti-MAG rabbit antisera. In a two-color immunofluorescence study, it seems that MAG-positive cells are a subset of Leu-7 positive cells and most but not all MAG-positive cells reveal Leu-7^+ Leu-11^+. In some patients with multiple sclerosis, the percentage of MAG positive cells was reduced but which was not related to disease activity and was not a pathognomonic feature of multiple sclerosis. Four of 14 patients with multiple sclerosis showed a normal number of Leu-7 positive cells and a reduced number of MAG positive cells. Human mononuclear cells conjugated with K-562, target cells of human natural killer（NK）cells, were stained by anti-Leu-7 and also by anti-MAG antisera. The remaining human NK activity after treatment of anti-MAG monoclonal mouse IgM or anti-Leu-7 antibody and complement revealed 13.4% and 15.1%, respectively（untreated NK activity was 40.8%）but NK activity could be abrogated by anti-Leu-11 and complement. Our findings suggest that“MAG”is a useful marker of human NK cells and NK cells may be influenced by anti-MAG antibody if it is found in the sera as anti-lymphocytotoxic antibody.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "146556", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Tanaka, Masami"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "田中, 正美"}], "nameIdentifiers": [{"nameIdentifier": "146555", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "100(10)_585-601.pdf", "filesize": [{"value": "2.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2100000.0, "url": {"label": "100(10)_585-601.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/24551/files/100(10)_585-601.pdf"}, "version_id": "aa258ab6-f544-4bd5-9792-881171aa2fca"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "myelin-associated glycoprotein", "subitem_subject_scheme": "Other"}, {"subitem_subject": "natural killer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "demyelination", "subitem_subject_scheme": "Other"}, {"subitem_subject": "lymphocytotoxic antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ナチュラルキラー", "subitem_subject_scheme": "Other"}, {"subitem_subject": "脱髄", "subitem_subject_scheme": "Other"}, {"subitem_subject": "抗リンパ球抗体", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "抗Myelin-associated glycoprotein抗体により染色されるヒト末梢血単核球の性質", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "抗Myelin-associated glycoprotein抗体により染色されるヒト末梢血単核球の性質"}, {"subitem_title": "抗Myelin-associated glycoprotein抗体により染色されるヒト末梢血単核球の性質", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1241"], "permalink_uri": "http://hdl.handle.net/10191/35499", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-12-11"}, "publish_date": "2015-12-11", "publish_status": "0", "recid": "24551", "relation": {}, "relation_version_is_last": true, "title": ["抗Myelin-associated glycoprotein抗体により染色されるヒト末梢血単核球の性質"], "weko_shared_id": null}