{"_buckets": {"deposit": "ecb900cc-b2c2-49db-ba35-2da84e72b70f"}, "_deposit": {"id": "24551", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "24551"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00024551"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Characterization of human peripheral lymphocytes stained by anti-myelin-associated glycoprotein"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1986-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "601", "bibliographicPageStart": "585", "bibliographicVolumeNumber": "100", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "We found that the same antigenic determinant as myelin-associated glycoprotein \uff08MAG) of human central nervous system \uff08CNS\uff09exists on the cell surface of mononuclear cells in human peripheral blood, which was counted to 8.5\u00b12.7% of mononuclear cells from 41 healthy individuals when stained by anti-MAG rabbit antisera. In a two-color immunofluorescence study, it seems that MAG-positive cells are a subset of Leu-7 positive cells and most but not all MAG-positive cells reveal Leu-7^+ Leu-11^+. In some patients with multiple sclerosis, the percentage of MAG positive cells was reduced but which was not related to disease activity and was not a pathognomonic feature of multiple sclerosis. Four of 14 patients with multiple sclerosis showed a normal number of Leu-7 positive cells and a reduced number of MAG positive cells. Human mononuclear cells conjugated with K-562, target cells of human natural killer\uff08NK\uff09cells, were stained by anti-Leu-7 and also by anti-MAG antisera. The remaining human NK activity after treatment of anti-MAG monoclonal mouse IgM or anti-Leu-7 antibody and complement revealed 13.4% and 15.1%, respectively\uff08untreated NK activity was 40.8%\uff09but NK activity could be abrogated by anti-Leu-11 and complement. Our findings suggest that\u201cMAG\u201dis a useful marker of human NK cells and NK cells may be influenced by anti-MAG antibody if it is found in the sera as anti-lymphocytotoxic antibody.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "146556", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Tanaka, Masami"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u7530\u4e2d, \u6b63\u7f8e"}], "nameIdentifiers": [{"nameIdentifier": "146555", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "100(10)_585-601.pdf", "filesize": [{"value": "2.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2100000.0, "url": {"label": "100(10)_585-601.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/24551/files/100(10)_585-601.pdf"}, "version_id": "aa258ab6-f544-4bd5-9792-881171aa2fca"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "myelin-associated glycoprotein", "subitem_subject_scheme": "Other"}, {"subitem_subject": "natural killer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "demyelination", "subitem_subject_scheme": "Other"}, {"subitem_subject": "lymphocytotoxic antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30ca\u30c1\u30e5\u30e9\u30eb\u30ad\u30e9\u30fc", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u8131\u9ac4", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u6297\u30ea\u30f3\u30d1\u7403\u6297\u4f53", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u6297Myelin-associated glycoprotein\u6297\u4f53\u306b\u3088\u308a\u67d3\u8272\u3055\u308c\u308b\u30d2\u30c8\u672b\u68a2\u8840\u5358\u6838\u7403\u306e\u6027\u8cea", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u6297Myelin-associated glycoprotein\u6297\u4f53\u306b\u3088\u308a\u67d3\u8272\u3055\u308c\u308b\u30d2\u30c8\u672b\u68a2\u8840\u5358\u6838\u7403\u306e\u6027\u8cea"}, {"subitem_title": "\u6297Myelin-associated glycoprotein\u6297\u4f53\u306b\u3088\u308a\u67d3\u8272\u3055\u308c\u308b\u30d2\u30c8\u672b\u68a2\u8840\u5358\u6838\u7403\u306e\u6027\u8cea", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1241"], "permalink_uri": "http://hdl.handle.net/10191/35499", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-12-11"}, "publish_date": "2015-12-11", "publish_status": "0", "recid": "24551", "relation": {}, "relation_version_is_last": true, "title": ["\u6297Myelin-associated glycoprotein\u6297\u4f53\u306b\u3088\u308a\u67d3\u8272\u3055\u308c\u308b\u30d2\u30c8\u672b\u68a2\u8840\u5358\u6838\u7403\u306e\u6027\u8cea"], "weko_shared_id": null}