@article{oai:niigata-u.repo.nii.ac.jp:00024389,
 author = {星野, 重幸 and 河本, 広志 and 来生, 哲 and 荒川, 正昭},
 issue = {12},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Dec},
 note = {We investigated the bronchial hyperresponsiveness to methacholine chloride by Astograph in patients with bronchial asthma, chronic obstructive lung disease, sarcoidosis and interstitial pneumonia. The results were as follows. 1）Bronchial sensitivity （Dmin） was highest in patients with bronchial asthma and significant difference was observed between patients with bronchial asthma and normal subjects （p＜0.001）. This suggests that bronchial sensitivity can be well assessed by Astograph. Significant differences were also observed between normal subjects and patients with COLD, sarcoidosis and interstitial pneumonia. 2）No significant difference in Dmin was observed between patients with atopic asthma and nonatopic asthma. 3）Dmin was significantly higher in patients with moderate asthma than in those with mild asthma. 4）Significant correlations were observed between Grs c and Dmin （p＜0.001） and between Grs c and SGrs （p＜0.05） in patients with bronchial asthma, but no significant correlations were observed between Dmin and SGrs or SGrs/Grs c.},
 pages = {765--775},
 title = {気管支喘息, 慢性閉塞性肺疾患, サルコイドージスおよび間質性肺炎における気道過敏性に関する研究 : アストグラフによる塩化メタコリン吸入試験},
 volume = {100},
 year = {1986}
}