@article{oai:niigata-u.repo.nii.ac.jp:00024238, author = {金沢, 宏 and 大関, 一 and 矢沢, 正知 and 江口, 昭治}, issue = {3}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Mar}, note = {Cardiopulmonary bypass (CPB), functioning as the pumping system and the gas exchange functions, is one of the important instruments in cardiovascular operations. But it has many unfavourable problems such as massive blood transfusion, hemodilution, abnormality of coagulation, etc. In fact, 5 or 6 units of blood are necessary to prime CPB in infant, child, and adult. After CPB, massive blood transfusion is necessary to keep good circulation, and to recover from hemodilution and abnormal coagulability. But autotransfusion is practiced in cases with ASD, ACBG, and mono valvular disase. This technique can reduce the side effect of blood transfusion, but is not appropriate for the case with long perfusion in open heart surgery, because of undesirable hemodilution and hypoproteinemia. At present, considerable volume of blood is necessary to operate CPB in cardiovascular surgery.}, pages = {180--184}, title = {6) 体外循環と輸血(シンポジウム 血液製剤の輸血適応と問題点, 1986年, 第420回新潟医学会例会)}, volume = {101}, year = {1987} }