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各種肝疾患における NK 活性の動向と NK 活性測定に関する基礎的検討
http://hdl.handle.net/10191/40692
http://hdl.handle.net/10191/4069267779828-37b2-48cb-8227-b4fe4bf5d61d
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-04-05 | |||||
タイトル | ||||||
タイトル | 各種肝疾患における NK 活性の動向と NK 活性測定に関する基礎的検討 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 各種肝疾患における NK 活性の動向と NK 活性測定に関する基礎的検討 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | NK Activity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | K562 Cell | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Liver Disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Interferon Therapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | NK 活性 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | K562 細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 肝疾患 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | インターフェロン療法 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | The Fundamental Studies on Natural Killer (NK) Assay and the Clinical Investigation NK Activity in Various Liver Diseases | |||||
著者 |
吉田, 俊明
× 吉田, 俊明 |
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著者別名 | ||||||
識別子 | 141469 | |||||
識別子Scheme | WEKO | |||||
姓名 | Yoshida, Toshiaki | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The methodology of NK assay was investigated using K562 cell line as target cells and NK activity of peripheral blood lymphocytes (PBL) obtained from patients with various liver diseases was measured. The susceptibility of K562 cells to NK cell depended on their cell cycle phases, Therefore, it was suggested that NK activity of the same healthy donors should be measured simultaneously in each assay. The NK activity of PBC, as well as LC, was significantly lower than that of other liver diseases. Any suppressive factors against NK activity, however, were not detected in sera from PBC. Serial change of NK activity of 11 HBsAg-positive patients treated with interferon (IFN) was investigated. The augmented NK activity was observed only in the first and second week during IFN treatment and it returned to previous level after the fourth week. Patients with HCC who showed lower NK activity had poorer life prognosis than those who possessed normal NK activity. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 102, 号 4, p. 220-228, 発行日 1988-04 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |