@article{oai:niigata-u.repo.nii.ac.jp:00023451,
 author = {須田, 陽子},
 issue = {6},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Jun},
 note = {The characteristic of esophageal varices and anticipation of risky varies were investigated in patients with primary biliary cirrhosis (PBC). Endoscopically, Two groups of patients were distinguished: Group I comprised of 18 patients without esophageal varices and group II comprised of 12 patients with risky varices. Two groups were compared clinically, serologically and histologically. The results were as follows; 1) Hemostasis of variceal hemorrhage was very difficult in spite of giving various treatment. 2) On hemodynamic study by percutaneous transhepatic portal vein catheterization, portal venous pressure was very high and collateral channel was only coronary vein leading to the esophageal varices in patients with PBC. 3) Histologically dilatation of the portal vein branches and aberrant vasculature in portal vein lesions and parenchyma were observed in many specimens from early histological stage. 4) Variceal hemorrhage was experienced even in histologically early stage (stage I). 5) Risky varices were observed in patients of asymptomatic PBC, and hematemesis was the initial symptom in two patients. 6) Bleeding from esophageal varices was one of the most common causes of death in the patients with PBC. 7) When remarkable splenomegaly was observed, risky varices were anticipated. 8) ALP was considered to be the marker of the esophageal varices being in the accelerated phase. We should observe the esophageal varices more carefully when serum concentrations of ALP were more than 2,000IU/L.},
 pages = {344--352},
 title = {原発性胆汁性肝硬変における食道静脈瘤の特異性に関する臨床的研究},
 volume = {102},
 year = {1988}
}