@article{oai:niigata-u.repo.nii.ac.jp:00023301, author = {星山, 真理 and 岩渕, 三哉 and 鬼島, 宏 and 高木, 卯一}, issue = {10}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Oct}, note = {The autopsied case of septic shock associated with severe hypoglycemia was rarely reported. In this paper a case report was presented on a 67-year-old man who died of septic shock with hypoglycemia (BG 13mg/dl). The pathological diagnosis was hepatic cirrhosis and acute bacterial pneumonia. There was no evidence of insulinoma, β-cell hyperplasia and other endocrine organ abnormalities. Levels of serum IRI, growth hormone and plasma cortisol were elevated. Several mechanisms of hypoglycemia and hyperinsulinemia in this case are considered; (i) decreased hepatic glycogen storage due to the hepatic cirrhosis, (ii) increased catabolic state and glucose consumption in the peripheral tissues under the endotoxin shock state, (iii) inhibition of gluconeogenesis and acceleration of glucogenolysis in the liver, (iv) influence of the hepatic glucose metabolism induced by endotoxin, and (v) release and leakage of some hormones from shocked organs. Septic shock is critical and rapidly progressive.}, pages = {646--650}, title = {著明な低血糖を呈した敗血症性ショックの一剖検例 : 内分泌所見について}, volume = {102}, year = {1988} }