@article{oai:niigata-u.repo.nii.ac.jp:00022955,
 author = {上野, 欣一},
 issue = {4},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Apr},
 note = {Quantitative histomorphometric analyses of iliac bone were performed after tetracycline double bone labeling in 59 females with postmenopausal or senile osteoporosis and in 36 healthy males and females. Ten static and dynamic parameters of iliac cancellous bone area were measured with semi-automatic image analyzer. Furthermore, the number and degree of spinal compression fracture were evaluated with X-ray films of spine. The osteoporotic patients were divided into three groups according to their age (i.e. 50-65 y.o. into group A, 66-74 y.o. into group B, over 75 y.o. into group C). Healthy young females (14-47 y.o.) out of 36 healthy males and females were selected as a control group (group N). In comparison of osteoporotic groups (group A, B and C) with group N, cancellous bone volume (BV/TV), mineral apposition rate (MAR), wall thickness (W. Th), trabecular thickness (Tb. Th) and bone formation rate per unit volume of tissue (BFR/TV) were significantly decreased and trabecular separation (Tb. Sp) was significantly increased in the osteoporotic groups. However, the difference in these parameters was not significant between three osteoporotic groups. In group C, consisted of senile osteoporosis, total resorption surface (ES/BS) was significantly increased and relative osteoid surface (OS/BS) and fractional double-labeled surface (dLS/BS) tended to decrease in comparison with group A, consisted of postmenopausal osteoporosis. These results were interpreted as suggesting that senile osteoporosis was more markedly associated with the uncoupling between bone resorption and formation. No significant correlation was proved between cancellous bone volume (BV/TV) and the number or degree of spinal compression fracture.},
 pages = {310--322},
 title = {一次性骨粗鬆症における骨動態の組織形態計測学的研究 : 骨量と脊椎圧迫骨折との関連},
 volume = {103},
 year = {1989}
}