@article{oai:niigata-u.repo.nii.ac.jp:00022946, author = {羽柴, 正夫}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {Anaphylactic and anaphylactoid reactions are life-threatening hypersensitivities characterized by sudden and dramatic changes in cardiovascular, respiratory and cutaneous systems, demonstrating severe hypotension, syncope, dyspnea and/or urticaria. These reactions are activated by both immunological and non-immunological mechanisms. Agents commonly implicated in these reactions are antibiotics, anesthetics, blood products, antisera, anti-inflammatory agents, iodinated radiocontrast drugs, venoms and so on. Treatment must begin as soon as anaphylaxis is suspected. Airway maintenance, oxygen administration, intravenous fluid infusion and pharmacological therapy that should be started with epinephrine are essential. To prevent anaphylaxis, careful medical histories should be obtained prior to the administration of drugs. When a severe reaction develops, aggresive and prompt treatment is necessary to avoid disastrous outcome.}, pages = {243--248}, title = {1) 薬物ショックとその対策(シンポジウム 各科におけるショックとその対策, 第440回新潟医学会)}, volume = {103}, year = {1989} }