WEKO3
アイテム
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5) CSF(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会)
http://hdl.handle.net/10191/41254
http://hdl.handle.net/10191/41254d9be2ada-b714-454b-8e0e-c0e7b6119b14
名前 / ファイル | ライセンス | アクション |
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103(5)_363-367.pdf (2.3 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-04-11 | |||||
タイトル | ||||||
タイトル | 5) CSF(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会) | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 5) CSF(シンポジウム Growth Factorの基礎と臨床, 第434回新潟医学会) | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | human G-CSF | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Immunohistology | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | messenger RNA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ヒトG-CSF | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 免疫組織学 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mRNA | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Colony Stimulating Factor : The distribution in human organs(Recent Advances in Research on the Cell Growth Factors) | |||||
著者 |
鳥羽, 健
× 鳥羽, 健× 古川, 達雄× 岸, 賢治× 伊藤, 正毅× 森山, 美昭× 柴田, 昭× 福田, 剛明 |
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著者別名 | ||||||
識別子 | 138477 | |||||
識別子Scheme | WEKO | |||||
姓名 | Toba, Ken | |||||
著者別名 | ||||||
識別子 | 138478 | |||||
識別子Scheme | WEKO | |||||
姓名 | Furukawa, Tatsuo | |||||
著者別名 | ||||||
識別子 | 138479 | |||||
識別子Scheme | WEKO | |||||
姓名 | Kishi, Kenji | |||||
著者別名 | ||||||
識別子 | 138480 | |||||
識別子Scheme | WEKO | |||||
姓名 | Ito, Seiki | |||||
著者別名 | ||||||
識別子 | 138481 | |||||
識別子Scheme | WEKO | |||||
姓名 | Moriyama, Yoshiaki | |||||
著者別名 | ||||||
識別子 | 138482 | |||||
識別子Scheme | WEKO | |||||
姓名 | Shibata, Akira | |||||
著者別名 | ||||||
識別子 | 138483 | |||||
識別子Scheme | WEKO | |||||
姓名 | Fukuda, Takeaki | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The cloning of human granulocyte colony-stimulating factor (hG-CSF) has been recently established. Thereafter, purified recombinant hG-CSF have been able to be used for study. However there is no report demonstrating the distribution of G-CSF in human organs. In order to clarify this point, we made ginea pig antisera against hG-CSF, and immunohistological studies were done. A human CSF producing cancer cell line SPT-3.25, established in our laboratory, was also examined as a positive control. The immunohistological study revealed that G-CSF like substance is present in SPT-3.25 cells, chief cells of gastric gland, exocrine cells of pyloric gland, salivary grand and pancreas and syncytial trophoblast of placenta. On the other hand, it was absent in liver, spleen, lung, kidney and lymph node. For the purpose of determining the expression hG-CSF messenger RNA, northern blotting analysis was then done using 40-mer oligo DNA encoding hG-CSF. Poly (A^+) RNA extracted from SPT-3.25 was hibridezed with the probe, and the messenger size appeared to be 1.5kb. However none of poly (A^+) RNA extracted from spleen, gastric mucosa and placenta was found to be hibridized with it. Based on this preliminary study, G-CSF content must be analized in the extract of organs which were positively stained with anti G-CSF antisera, to determine if these organs be able to produce G-CSF in vivo. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 103, 号 5, p. 363-367, 発行日 1989-05 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |