{"_buckets": {"deposit": "6d466b54-b469-40d0-b758-51a386a0ca04"}, "_deposit": {"id": "22911", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22911"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022911"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Colony Stimulating Factor : The distribution in human organs(Recent Advances in Research on the Cell Growth Factors)"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "367", "bibliographicPageStart": "363", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "The cloning of human granulocyte colony-stimulating factor (hG-CSF) has been recently established. Thereafter, purified recombinant hG-CSF have been able to be used for study. However there is no report demonstrating the distribution of G-CSF in human organs. In order to clarify this point, we made ginea pig antisera against hG-CSF, and immunohistological studies were done. A human CSF producing cancer cell line SPT-3.25, established in our laboratory, was also examined as a positive control. The immunohistological study revealed that G-CSF like substance is present in SPT-3.25 cells, chief cells of gastric gland, exocrine cells of pyloric gland, salivary grand and pancreas and syncytial trophoblast of placenta. On the other hand, it was absent in liver, spleen, lung, kidney and lymph node. For the purpose of determining the expression hG-CSF messenger RNA, northern blotting analysis was then done using 40-mer oligo DNA encoding hG-CSF. Poly (A^+) RNA extracted from SPT-3.25 was hibridezed with the probe, and the messenger size appeared to be 1.5kb. However none of poly (A^+) RNA extracted from spleen, gastric mucosa and placenta was found to be hibridized with it. Based on this preliminary study, G-CSF content must be analized in the extract of organs which were positively stained with anti G-CSF antisera, to determine if these organs be able to produce G-CSF in vivo.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "138477", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Toba, Ken"}]}, {"nameIdentifiers": [{"nameIdentifier": "138478", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Furukawa, Tatsuo"}]}, {"nameIdentifiers": [{"nameIdentifier": "138479", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kishi, Kenji"}]}, {"nameIdentifiers": [{"nameIdentifier": "138480", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ito, Seiki"}]}, {"nameIdentifiers": [{"nameIdentifier": "138481", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Moriyama, Yoshiaki"}]}, {"nameIdentifiers": [{"nameIdentifier": "138482", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Shibata, Akira"}]}, {"nameIdentifiers": [{"nameIdentifier": "138483", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Fukuda, Takeaki"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": 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