@article{oai:niigata-u.repo.nii.ac.jp:00022874,
 author = {小出, 武比古},
 issue = {6},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Jun},
 note = {Hemophilias A and B are the most common hereditary hemorrhagic disorders that are caused by a deficiency or dysfunction of coagulation factors VIII and IX, respectively. Recently, both the factor VIII and the factor IX genes have been cloned and well characterized, and three and five intragenic RFLPs (restriction fragment length polymorphisms) of the factor VIII and the factor IX genes, respectively, have been identified. These RFLPs can be successfully used for prenatal diagnosis and carrier detection of hemophilia A. DNA diagnosis of hemophilia B in Japanese, however, is not successful due to the absence of common polymorphisms thus far identified in Caucasians.},
 pages = {457--461},
 title = {5) 血友病のDNA診断(シンポジウム 遺伝子工学による病因解析とその診断, 第435回新潟医学会)},
 volume = {103},
 year = {1989}
}