@article{oai:niigata-u.repo.nii.ac.jp:00022768, author = {田中, 英城}, issue = {10}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Oct}, note = {Healing of full thickness articular defects (1 mm in diameter, 4 mm in depth) on the weight bearing vs. non-weight bearing portion of the knee joints of adolescent rabbits by application of CPM (Continuous Passive Motion) was investigated in comparison with that by post-operative intermittent active motion or immobilization. The shape of the surface and nature of the reparative tissue between tidemark and the articular surface were assessed by light microscopy weekly up to 4 weeks after creation of cartilage defects. The following results were obtained 1. Knee joint cartilage defects on the weight bearing portion after application of CPM for 4 weeks were usually repaired with fibrous tissue. The repaired surface left slight depression from the adjacent articular surface. There was no significant difference in the nature of the reparative tissue histologically examined after having been treated with CPM, intermittent active motion or immobilization. 2. 47% of the defects which were made on 4 different non-weight bearing portions, in the same model as that of Salter, were repaired with hyaline cartilage after application of CPM for 4 weeks. There was no statistically significant difference between this and Salter's result. 3. The repair of the cartilage defects on the patellofemoral portion of the femur were statistically better than that on the weight bearing cartilage of the femur. In summary, healing of full thickness articular cartilage defects on the weight bearing portion is poorer than that on the non-weight bearing portion of the knee joints of adolescent rabbits by application of CPM.}, pages = {823--841}, title = {持続他動運動による滑膜関節軟骨切除部分の修復に関する実験的研究 : 特に荷重部と非荷重部における修復の比較}, volume = {103}, year = {1989} }