@article{oai:niigata-u.repo.nii.ac.jp:00022753, author = {渡辺, 元}, issue = {11}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Nov}, note = {The effect of microelectrical current on internal remodeling and anodic oxidation in long tubular bone was examined using femurs of 24 adult mongrel dogs. To minimize anodic oxidation, obtaining effective stimulation, a generator with pulse current of charge recovery type was made. The femur of dog was stimulated for four weeks by various waveform current, i.e., pulse current of charge recovery type, 1 Hz 10 uA; pulse current, 1 Hz, 10 uA; direct current, 10 uA; and alternating rectangular pulse, 1 Hz, 10 uA. The effect was evaluated by histomorphometric parameters in terms of number of resorption cavities (Ar), number of osteons with osteoid seam (osAf) and area of bone resorption around the electrode. The following results were obtained. 1. A significant increase of internal remodeling of bone was noted in the femur as stimulated by pulse current of charge recovery type as compared with the nonstimulated femur. 2. The smallest area of bone resorption was shown in a portion around anode of pulse current of charge recovery type pulse, which occurred less anodic oxidation, and larger area was also observed in order of pulse current and direct current. No significant difference of the area of bone resorption was shown among portions around cathode and anode of pulse current of charge recovery type stimulation and electrodes of alternating rectangular pulse. 3. Using pulse current of charge recovery type the internal remodeling of bone around cathode of femur, in which both cathode and anode were inserted, showed a more increase than that around cathode, which was inserted only in femur, and anode was placed in subcutaneous tissue of the thigh. 4. The internal remodeling around cathode of pulse curret of charge recovery type pulse stimulation showed a significant increase than that around the electrode of alternating rectangular pulse stimulation.}, pages = {923--935}, title = {骨皮質のInternal Remodelingを促進し陽極酸化を防止できる骨通電刺激法の実験的研究}, volume = {103}, year = {1989} }