@article{oai:niigata-u.repo.nii.ac.jp:00022680,
 author = {遠藤, 道仁},
 issue = {12},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Dec},
 note = {Many investigators have suggested that prostaglandins (PGs) may have immunoregulatory function at the implantation site. In this study, in order to identify prostaglandin producing cells in human endometrium in non-pregnant state and the decidua basalis, an immuno-peroxidase staining was applied in their tissue sections using rabbit anti-PGE_2 and -PGF_<2α> antisera and mouse monoclonal antibodies. The following results were obtained. 1) The localization of PGE_2-positive cells in the endometrium was almost the same as that of PGF_<2α>-positive cells. As most of them were positive for HLA-DR and Leu-M_3, they were considered to be monocytes/macrophages. 2) In non-pregnant endometrium, PGE_2-positive cells were more numerous in the secretory phase than in the proliferative phase, showing an increasing tendency after the implantation. 3) The number of PGE_2 positive cells in the decidua was slightly smaller than that in secretory phase, showing a gradual decrease with gestational age. 4) None of PGE_2 or PGF_<2α>-positive cells reacted with anti-Leu-1 antibody. 5) Most of PGE_2-positive cells were stained with anti-HLA-DR in non-pregnant state, while some of PGE_2-positive cells were not stained with anti-HLA-DR in the decidua of the first trimester.},
 pages = {988--992},
 title = {非妊子宮内膜及び着床部におけるプロスタグランディン産生細胞に関する研究},
 volume = {103},
 year = {1989}
}