{"created":"2021-03-01T06:27:51.495946+00:00","id":22679,"links":{},"metadata":{"_buckets":{"deposit":"e5b0e963-18a5-401b-8af1-7789f7e1a0d5"},"_deposit":{"id":"22679","owners":[],"pid":{"revision_id":0,"type":"depid","value":"22679"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00022679","sets":["453:456","471:537:538:1203"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Experimental Allergic Encephalomyelitis(Autoimmune Diseases)"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1989-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageEnd":"987","bibliographicPageStart":"985","bibliographicVolumeNumber":"103","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Experimental allergic encephalomyelitis (EAE) is a T-cell mediated autoimmune disease inducible by immunization with brain specific antigens such as myelin basic protein (MBP) in complete Freund's adjuvant (CFA). Using EAE as an experimental model for human autoimmune disorders, we show here several experimental approaches and the results obtained by these approaches. They include 1) immunohistochemical examination of the lesions of EAE, 2) double immunofluorescent staining of the tissue in order to identify the nature of cells of interest, 3) passive EAE which facilitutes the examination of developing lesions of EAE, and 4) radiation bone marrow chimeras which were prepared for the detection of bone marrow-derived cells in the central nervous system. We also introduced limiting dilution analysis of MBP-reactive T cells and thymus-grafted chimeras.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"137511","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Matsumoto, Yoh"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松本, 陽"}],"nameIdentifiers":[{"nameIdentifier":"137510","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-19"}],"displaytype":"detail","filename":"103(12)_985-987.pdf","filesize":[{"value":"626.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"103(12)_985-987.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/22679/files/103(12)_985-987.pdf"},"version_id":"ad4254e3-e15b-4cd5-8ed3-8d76263a3234"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Experimental allergic encephalornyelitis","subitem_subject_scheme":"Other"},{"subitem_subject":"EAE","subitem_subject_scheme":"Other"},{"subitem_subject":"Immunohistochemistry","subitem_subject_scheme":"Other"},{"subitem_subject":"Limiting dilution analysis","subitem_subject_scheme":"Other"},{"subitem_subject":"Bone marrow chimera","subitem_subject_scheme":"Other"},{"subitem_subject":"アレルギー性脳髄炎","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫組織化学","subitem_subject_scheme":"Other"},{"subitem_subject":"限界稀釈法","subitem_subject_scheme":"Other"},{"subitem_subject":"骨髄キメラ","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"6) アレルギー性脳脊髄炎(シンポジウム 自己免疫疾患, 第445回新潟医学会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"6) アレルギー性脳脊髄炎(シンポジウム 自己免疫疾患, 第445回新潟医学会)"},{"subitem_title":"6) アレルギー性脳脊髄炎(シンポジウム 自己免疫疾患, 第445回新潟医学会)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1203"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-04-13"},"publish_date":"2016-04-13","publish_status":"0","recid":"22679","relation_version_is_last":true,"title":["6) アレルギー性脳脊髄炎(シンポジウム 自己免疫疾患, 第445回新潟医学会)"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:53:01.306005+00:00"}