@article{oai:niigata-u.repo.nii.ac.jp:00022529, author = {宇井, 政彦}, issue = {3}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Mar}, note = {The cardiovascular autonomic neuropathy was studied by measurement of variation in R-R intervals of ECG at deep breathing, maximum increase in heart rate at standing, and presence/absence of orthostatic hypotension, in 79 diabetic patients and 30 non-diabetic hemodialysis patients. The results were as follows: 1) The development of cardiovascular autonomic neuropathy in diabetes was divided into four stages: group A without autonomic neuropathy, group B with parasympathetic neuropathy, group C with parasympathetic and α-adrenergic neuropathy, gourp D with parasympathetic and α- and β-adrenergic neuropathy. 2) The non-diabetic hemodialysis patients had no parasympathetic neuropathy. Dialysis-induced hypotension probably reflected a sympathetic insufficiency, that is, an impairment of the vaso constriction response of the vascular wall. 3) The pathophysiology of diabetic patients with orthostatic hypotension resembled that of idiopathic orthostatic hypotension (IOH). On the other hand, the pathophysiology of non-diabetic patients with orthostatic hypotension after a dialysis (dialysis-induced hypotension group II, that is, group G) resembled that of patients with sympathotonic orthostatic hypotension (SOH).}, pages = {188--198}, title = {心拍数変動を用いた心臓血管系の自律神経障害に関する研究 : 糖尿病ならびに非糖尿病透析患者を中心として}, volume = {104}, year = {1990} }