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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第104巻第4号

小児特発性ネフローゼ症候群の免疫異常における亜鉛の関与についての研究(第2編) : 特発性ネフローゼ症候群患児リンパ球の免疫グロブリン産生能に対する亜鉛の効果

http://hdl.handle.net/10191/33846
http://hdl.handle.net/10191/33846
c477d743-d0c3-4c1f-9139-5f66e475ea1d
名前 / ファイル ライセンス アクション
104(4)_279-286.pdf 104(4)_279-286.pdf (1.6 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-11-04
タイトル
タイトル 小児特発性ネフローゼ症候群の免疫異常における亜鉛の関与についての研究(第2編) : 特発性ネフローゼ症候群患児リンパ球の免疫グロブリン産生能に対する亜鉛の効果
タイトル
言語 en
タイトル 小児特発性ネフローゼ症候群の免疫異常における亜鉛の関与についての研究(第2編) : 特発性ネフローゼ症候群患児リンパ球の免疫グロブリン産生能に対する亜鉛の効果
言語
言語 jpn
キーワード
主題Scheme Other
主題 idiopathic nephrotic syndrome
キーワード
主題Scheme Other
主題 zinc deficiency
キーワード
主題Scheme Other
主題 IgG production
キーワード
主題Scheme Other
主題 特発性ネフローゼ症候群
キーワード
主題Scheme Other
主題 亜鉛欠乏症
キーワード
主題Scheme Other
主題 IgG産生能
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Study of Zinc Metabolism and Immunological Disorder in Children with Idiopathic Nephrotic Syndrome (Part 2) : Effect of Zinc on the Synthesis of Immunoglobulin in Children with Idiopathic Nephrotic Syndrome
著者 五味, 崇行

× 五味, 崇行

WEKO 135828

五味, 崇行

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著者別名
識別子 135829
識別子Scheme WEKO
姓名 Gomi, Takayuki
抄録
内容記述タイプ Abstract
内容記述 The effect of zinc to immunoglobulin synthesis of B lymphocytes and lymphocyte blastgenesis on idiopathic nephrotic syndrome (INS) (frequent relapser type) was performed. Lymphocytes of INS patients were cultured with various concentration (12.5, 25, 50, 100, 200 μM/L) of zinc sulfate solution. Then the patients were given zinc sulfate (1~2 mg/kg) for more than twelve weeks, and immunoglobulin synthesis was measered every month. Lymphocyte blastgenesis was most increased when 100 μM/L of zinc solution (about 150 μg/dl in GIT medium) was added. Con A stimulation increased it 1.79 times, PHA-P 1.10 times and Sac 1 1.61 times. Spontaneous IgG synthesis was slightly increased when 100 μM/L of zinc solution (about 150 μg/dl in GIT medium) was added. And spontaneous IgG synthesis of whole lymphocytes was slightly increased by zinc. However PWM stimulated IgG sunthesis, and IgA and IgM synthesis was not increased by adding zinc solution. When zinc sulfate was administrated orally, IgG synthesis was significantly increased 4~5 weeks later, whereas IgA and IgM synthesis were not. These findings suggest that zinc is clinically important for the IgG synthesis.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 104, 号 4, p. 279-286, 発行日 1990-04
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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