@article{oai:niigata-u.repo.nii.ac.jp:00022342, author = {浅見, 直 and 橋本, 尚士 and 鳥谷部, 森 and 中野, 徳 and 笹川, 冨士雄 and 堺, 薫}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {In neonates serum total cholesterol levels increased with the advance in age from birth to 5-6 days of age. Hypercholesterolemic neonates, discovered on neonatal screening, showed also high cholesterol levels at three months of age, and the incidence of hypercholesterolemia was higher in their parents than in normal adults. A significant correlation was found betwee the atherogenic indices of the hypercholesterolemic infants and their fathers. Serum lipid levels were increased in patients with idiopathic nephrotic syndrome (INS) in relapses as compared with controls. Of interest was a significant increase in serum apoprotein E levels in patients with INS in remission for over 3 years as compared with controls, which implying some role of apo E in increasing serum cholesterol levels in INS. An inverse correlation was found between the levels of serum total cholesterol and blood glutathione concentrations. In rat experiments, the plasma cholesterol concentrations in the glutathione administered group were lower than those in the group without glutathione, however, the difference did not reach a statistical significance. More studies are needed to reach a valid conclusion on the cholesterol-lowering effect of glutathione.}, pages = {254--259}, title = {3) 小児疾患における血清脂質とアポリポ蛋白およびグルタチオン代謝の関連(シンポジウム 各科領域における脂質代謝異常, 第447回新潟医学会)}, volume = {104}, year = {1990} }