@article{oai:niigata-u.repo.nii.ac.jp:00022341, author = {三井田, 孝}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {We examined the relationship between abnormal lipoprotein metabolism and coronary atherosclerosis in 120 patients with angiographically proven coronary artery disease (CAD: 97 males and 23 females, 58.7±7.4 years and 63.0±6.6 years, respectively). The incidence of type II hyperlipidemia was 25.8% in males and 43.5% in females. In the male CAD group, type II hyperlipidemia seemed to be related to the earlier onset of CAD (below 50 years). VLDL and LDL lipid levels were significantly higher in the male CAD group than in the control group (p<0.001). IDL-cholesterol level was significantly higher in the former than that in the latter (p<0.05). Elevated IDL-cholesterol level seemed to be closely associated with type IIb hyper-lipidemia. HDL2-cholesterol, HDL2-phospholipid, HDL2-apolipoprotein A-I and HDL3-phospholipid levels were significantly lower in the male CAD group than those in the control group (p<0.05). In the CAD group, HDL2-cholesterol, HDL2-phospholipid and HDL2-apolipoprotein A-I levels were correlated significantly and negatively with serum triglyceride level (p<0.05). These data suggested that abnormal lipoprotein metabolism might be one of the promotive factors of coronary atherosclerosis.}, pages = {248--253}, title = {2) 冠動脈疾患におけるリポ蛋白代謝異常(シンポジウム 各科領域における脂質代謝異常, 第447回新潟医学会)}, volume = {104}, year = {1990} }