@article{oai:niigata-u.repo.nii.ac.jp:00022265, author = {服部, 晃 and 布施, 一郎 and 帯刀, 亘 and 柴田, 昭 and 伊藤, 粋子 and 渡部, 透 and 真田, えい and 小田, 勇司 and 滝沢, 慎一郎 and 矢沢, 光良 and 本間, 義章 and 飯泉, 俊雄 and 栗林, 和敏}, issue = {5}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {May}, note = {We have studied antiplatelet therapy by low-dose aspirin combined with ticlopidine under the control of platelet aggregation individually for secondary prevention of cerebral infarction (CI) and a preliminary results were reported. Eighty six patients (9 with TIA, 2 with RIND or 75 with CI) were treated by our protocol (Niigata Med. J. 101;642, 1987) for an average of 22 months. The doses of drugs were for aspirin at 10-75 (median 30) mg/day and for ticlopidine at 50-300 (median 200) mg/day. Cerebrovascular reattacks in all and recurrence of CI were 3.18% and 2.08% (patient x year), respectively. Mild non-fatal bleeding occurred in 4 patients. None of patients died during this study. In conclusion our method is turned out, at least, as effective as those reported by others, and seems safe in clinical application.}, pages = {381--386}, title = {微量アスピリン・チクロピヂン併用・患者別コントロールによる抗血小板療法の研究 : 第二報 脳梗塞再発防止についての中間報告}, volume = {104}, year = {1990} }