@article{oai:niigata-u.repo.nii.ac.jp:00022179, author = {高橋, 益広}, issue = {7}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jul}, note = {Myelodysplastic syndromes (MDS) include a wide range of hematological disorders which relate to ineffective hematopoiesis and have varying prognoses. Thus, establishing the prognostic factors, especially in cases with few blasts in the marrow, is important to define poor prognostic patients, so as to select the most appropriate therapy for these patients. In order to clarify the relationship between myelodysplastic morphologic features of marrow cells and prognoses and to define other prognostic factors, 124 patients with the FAB criteria of MDS were analysed. 57 patients with refractory anemia (RA), 5 with RA with ring sideroblasts (RARS), 25 with RA with excess of blasts (RAEB), 14 with chronic myelomonocytic leukemia (CMML) and 22 with RAEB in transformation (RAEB in T). Statistical analysis of all the patients with MDS or those with RA demonstrated that, besides the NAP score (significant only for all MDS), the percent of marrow erythroblasts, and lymphocytes (for all MDS and RA), the percentage of cells with mprphological abnormalities in individual cell lineages and the number of cell lineage showing atypia were significantly associated with the prognosis of all the MDS patients and those with RA.}, pages = {574--579}, title = {MDSの予後因子 : 特に血球形態異常(第20回新潟造血器腫瘍研究会十周年記念シンポジウム : 造血器腫瘍十年の歩み)}, volume = {104}, year = {1990} }