@article{oai:niigata-u.repo.nii.ac.jp:00022178, author = {内海, 治郎 and 浅見, 恵子 and 笹崎, 義弘}, issue = {7}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jul}, note = {92 patients with acute lymphocytic leukemia (ALL), 29 patients with acute nonlymphocytic leukemia (ANLL), and 6 patients with chronic myelogenous leukemia (CML) admitted to the Department of Pediatrics, Niigata Cancer Center Hospital between Jan. 1961 and Dec. 1988 are reviewed in this study. From 1981 to 1985, a complete remission in 96% of patients with ALL could be archived by remission induction therapies according to risk factors. The rate of continuous complete remission was 74% at 3 years and 57% at 5 years after a complete remission of the bone marrow. Cessation of maintenance therapies in 21 patients with ALL, who began remission induction therapies from 1977 to 1985 and continuous complete remission for more than 3 years, was undertaken. After cessation of therapies, the rate of continuous complete remission was 86% at 3 years and relapses were not seen for more than 3 years. Relapses occured in 4 patients from 2 to 26 months after cessation of therapies. The sites of the relapses were 3 case of bone marrow, and 1 case of bone marrow/CNS. Compared with ALL, the results of remission induction and maintenance therapies in childhood ANLL and CML are not as positive and bone marrow transplantation must be introduced in pediatrics.}, pages = {569--574}, title = {小児白血病(第20回新潟造血器腫瘍研究会十周年記念シンポジウム : 造血器腫瘍十年の歩み)}, volume = {104}, year = {1990} }