@article{oai:niigata-u.repo.nii.ac.jp:00022174, author = {藤原, 正博}, issue = {7}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jul}, note = {We use the bioclean room for the treatment of patients with acute leukemia since 1978 at the Niigata University School of Medicine. The bioclean room is turned out to be effective for prevention of pneumonia during the treatment of leukemia. Thirty patients with leukemia or aplastic anemia received bone marrow transplantation since 1981 at our institute. Sixteen of them experienced acute GVHD. One Patient died of severe disease but others had Grade I or II disease. Limited chronic GVHD was found in one-third of evaluable patients. Eighteen patients received marrow transplantation from ABO-incompatible sibling, and 3 of them had a delayed recovery of erythropoiesis. The probability of long-term survival is about 50%. Eight patients survive more than 3 years after transplant. All of them have no evidence of recurrence. Seventeen patients died of pulmonary complications, leukemia recurrence and other causes after marrow transplantation.}, pages = {551--554}, title = {治療 : 無菌室・骨髄移植(第20回新潟造血器腫瘍研究会十周年記念シンポジウム : 造血器腫瘍十年の歩み)}, volume = {104}, year = {1990} }