@article{oai:niigata-u.repo.nii.ac.jp:00022108,
 author = {広川, 恵子},
 issue = {8},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Aug},
 note = {Eleven patients with biliary atresia (BA) were studied about bone lesion with radiological changes in bone, serum level of 25-hydroxyvitamin D (25-OH-D), alkali-posphatase (Al-P) and other serum biochemical assay. All 4 patients who have prolongation of jaundice and 6 of seven patients without jaundice had rachitic changes on radiological examinations, and pathological fracture was observed in 3 of them. The 10 rachitic patients showed low serum 25-OH-D level and high Al-P level. Serum 25-OH-D level has been increasing as their growth in the 5 patients without jaundice. The 8 of rachitic patients have been treated by oral 1,25-dihydroxyvitamin D (1,25-OH_2-D). Now radiologically rachitic changes are not revealed in 7 patients, but 4 icteric patients have osteoporotic changes. Many of BA patients, especially icteric one can not excrete bile jouce enough to absorpt vitamin D and 25 hydroxylation in the liver will be disturbed in several degree, so it is necessary to observe postoperative BA patients for long time. On the other hand, 2 patients who received long term intravenous hyperalimentation (IVH) since neonatal period because of short bowel syndrome, have developed rickets. Their serum phosphate and vitamin D levels were low and Al-P levels were elevated. By increasing the amount of intravenous administration of calcium and posphate, biochemical data was normalized and radiological rachitic changes were disappeared. We must carefully administer IVH contents to develoaping infants.},
 pages = {635--639},
 title = {4) 小児外科患者にみられる代謝性骨疾患(シンポジウム 各科領域での代謝性骨疾患, 第439回新潟医学会)},
 volume = {104},
 year = {1990}
}