@article{oai:niigata-u.repo.nii.ac.jp:00021949, author = {高橋, 益広}, issue = {10}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Oct}, note = {Aplastic phase serum from a patient with aplastic crisis of hereditary spherocytosis, which was demonstrated to contain human parvovirus, inhibited in vitro erythroid colony formation almost completely and granulocyte-macrophage colony growth mildly. The suppressive effect of the serum was absolutely abrogated by adding convalescent phase serum from aplastic crisis, some normal sera, and human immunoglobulin products. Myeloid cell line KU-812, which is established from a patient with chronic myelogenous leukemia and possesses the ability of erythroid differentiation, was suppressed to form colonies by human parvovirus. These findings suggest that human parvovirus causing aplastic crisis of hemolytic anemia could be prevented or treated with human immunoglobulin products and that KU-812 might have the receptor for human parvovirus and could be a unique cell line in which parvoviruses replicate.}, pages = {818--823}, title = {3) ヒトパルボウイルスによる造血障害(シンポジウム 各科領域におけるウイルス病学の進歩, 第449回新潟医学会)}, volume = {104}, year = {1990} }