@article{oai:niigata-u.repo.nii.ac.jp:00021948,
 author = {松山, 東平 and 村上, 司},
 issue = {10},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Oct},
 note = {Polymorphonuclear leukocytes (PMN) exudation to the infected mucosa is noted as a characteristic feature of influenza virus infection. Since PMN-dependent mutagenesis of bacteria has been reported in correlation with reactive oxygen species generated from PMN. Cloned influenza A NWS (H1N1) virus multiplying in Madin-Darby canine kidney cells was treated with human peripheral PMN. Assays in the presence and absence of monoclonal antibody to the cloned virus indicated seven- to ten-fold increase in the frequency of monoclonal variants in the presence of PMN. Such mutagenic effect by PMN was abolished by addition of superoxide dismutase to the culture.},
 pages = {814--817},
 title = {2) インフルエンザウイルスの抗原変異 : 多形核白血球の役割(シンポジウム 各科領域におけるウイルス病学の進歩, 第449回新潟医学会)},
 volume = {104},
 year = {1990}
}