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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第105巻第4号

低分子ヘパリン(FR-860)のDICに対する臨床効果

http://hdl.handle.net/10191/38775
http://hdl.handle.net/10191/38775
efa16587-7e29-4793-8478-b1d3f24dd28d
名前 / ファイル ライセンス アクション
105(4)_272-278.pdf 105(4)_272-278.pdf (1.3 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-02-26
タイトル
タイトル 低分子ヘパリン(FR-860)のDICに対する臨床効果
タイトル
言語 en
タイトル 低分子ヘパリン(FR-860)のDICに対する臨床効果
言語
言語 jpn
キーワード
主題Scheme Other
主題 low molecular weight heparin (FR-860)
キーワード
主題Scheme Other
主題 DIC
キーワード
主題Scheme Other
主題 A multicenter cooperative study
キーワード
主題Scheme Other
主題 clinical effect
キーワード
主題Scheme Other
主題 低分子ヘパリン
キーワード
主題Scheme Other
主題 汎発性血管内血液凝固症
キーワード
主題Scheme Other
主題 多施設共同試験
キーワード
主題Scheme Other
主題 臨床効果
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Clinical Effect of Low Molecular Weight Heparin (FR-860) on DIC
著者 小熊, 豊

× 小熊, 豊

WEKO 131291

小熊, 豊

Search repository
桜川, 信男

× 桜川, 信男

WEKO 131292

桜川, 信男

Search repository
中川, 雅夫

× 中川, 雅夫

WEKO 131293

中川, 雅夫

Search repository
長谷川, 淳

× 長谷川, 淳

WEKO 131294

長谷川, 淳

Search repository
真木, 正博

× 真木, 正博

WEKO 131295

真木, 正博

Search repository
著者別名
識別子 131296
識別子Scheme WEKO
姓名 Oguma, Yutaka
著者別名
識別子 131297
識別子Scheme WEKO
姓名 Sakuragawa, Nobuo
著者別名
識別子 131298
識別子Scheme WEKO
姓名 Nakagawa, Masao
著者別名
識別子 131299
識別子Scheme WEKO
姓名 Hasegawa, Hiroshi
著者別名
識別子 131300
識別子Scheme WEKO
姓名 Maki, Masahiro
抄録
内容記述タイプ Abstract
内容記述 A study was intended to clarify the effectiveness of low molecular weight heparin (LMW Hp, FR-860;mean MW;4,400~5,600, KABI) on DIC. The research group was established among 49 nationwide institutes and 88 cases were challenged by FR-860 injection. The patients were divided into two groups and FR-860 was administered principally during 5 days with the doses of 75 U/kg/day in the I group (n=46) and 150 U/kg/day in the II group (n=42), respectively. Scoring points were defined according to the severity of bleeding symptoms, organ failures and abnormal coagulation-fibrinolytic examinations. By comparing the improvement ratio of these scores, therapeutic effect and clinical usefulness of FR-860 were evaluated into 5 types of excellently, moderately, slightly, unchanged (not useful) and aggravated (undesirable). The efficacy of FR-860 was evaluated in 27 and 29 cases of the I and II groups, respectively, excluding 32 cases such as treated with other drugs simultaneously. No significant difference was observed in the case profile between the two groups. 6 cases died due to the underlying diseases or complications other than DIC. In bleeding symptoms, 45.5 and 48.0% cases of the each group showed more than moderately improvement. In organ failures and coagulation-fibrinolytic examinations, 31.6 and 66.7% cases showed markedly or moderately improvement in the I group, while they remained 14.3 and 51.7% in the II group, respectively. And then, FR-860 revealed useful in 66.7 and 58.6% cases of the each group. These results demonstrate that FR-860 is effective on DIC with a dose of 75 U/kg/ day.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 105, 号 4, p. 272-278, 発行日 1991-04
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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