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アイテム
低分子ヘパリン（FR-860）のDICに対する臨床効果
http://hdl.handle.net/10191/38775
http://hdl.handle.net/10191/38775efa16587-7e29-4793-8478-b1d3f24dd28d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
105(4)_272-278.pdf (1.3 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-02-26 | |||||
| タイトル | ||||||
| タイトル | 低分子ヘパリン（FR-860）のDICに対する臨床効果 | |||||
| タイトル | ||||||
| タイトル | 低分子ヘパリン（FR-860）のDICに対する臨床効果 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | low molecular weight heparin (FR-860) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | DIC | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | A multicenter cooperative study | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | clinical effect | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 低分子ヘパリン | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 汎発性血管内血液凝固症 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 多施設共同試験 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 臨床効果 | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Clinical Effect of Low Molecular Weight Heparin （FR-860） on DIC | |||||
| 著者 |
小熊, 豊
× 小熊, 豊× 桜川, 信男× 中川, 雅夫× 長谷川, 淳× 真木, 正博 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 131296 | |||||
| 姓名 | Oguma, Yutaka | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 131297 | |||||
| 姓名 | Sakuragawa, Nobuo | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 131298 | |||||
| 姓名 | Nakagawa, Masao | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 131299 | |||||
| 姓名 | Hasegawa, Hiroshi | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 131300 | |||||
| 姓名 | Maki, Masahiro | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A study was intended to clarify the effectiveness of low molecular weight heparin （LMW Hp, FR-860；mean MW；4,400～5,600, KABI） on DIC. The research group was established among 49 nationwide institutes and 88 cases were challenged by FR-860 injection. The patients were divided into two groups and FR-860 was administered principally during 5 days with the doses of 75 U/kg/day in the I group （n＝46） and 150 U/kg/day in the II group （n＝42）, respectively. Scoring points were defined according to the severity of bleeding symptoms, organ failures and abnormal coagulation-fibrinolytic examinations. By comparing the improvement ratio of these scores, therapeutic effect and clinical usefulness of FR-860 were evaluated into 5 types of excellently, moderately, slightly, unchanged （not useful） and aggravated （undesirable）. The efficacy of FR-860 was evaluated in 27 and 29 cases of the I and II groups, respectively, excluding 32 cases such as treated with other drugs simultaneously. No significant difference was observed in the case profile between the two groups. 6 cases died due to the underlying diseases or complications other than DIC. In bleeding symptoms, 45.5 and 48.0% cases of the each group showed more than moderately improvement. In organ failures and coagulation-fibrinolytic examinations, 31.6 and 66.7% cases showed markedly or moderately improvement in the I group, while they remained 14.3 and 51.7% in the II group, respectively. And then, FR-860 revealed useful in 66.7 and 58.6% cases of the each group. These results demonstrate that FR-860 is effective on DIC with a dose of 75 U/kg/ day. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 105, 号 4, p. 272-278, 発行日 1991-04 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
