{"_buckets": {"deposit": "247bb987-ad49-4811-b4c1-880f557708bd"}, "_deposit": {"id": "21475", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "21475"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00021475", "sets": ["456", "1187"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Clinical Effect of Low Molecular Weight Heparin （FR-860） on DIC"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1991-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "278", "bibliographicPageStart": "272", "bibliographicVolumeNumber": "105", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "A study was intended to clarify the effectiveness of low molecular weight heparin （LMW Hp, FR-860；mean MW；4,400～5,600, KABI） on DIC. The research group was established among 49 nationwide institutes and 88 cases were challenged by FR-860 injection. The patients were divided into two groups and FR-860 was administered principally during 5 days with the doses of 75 U/kg/day in the I group （n＝46） and 150 U/kg/day in the II group （n＝42）, respectively. Scoring points were defined according to the severity of bleeding symptoms, organ failures and abnormal coagulation-fibrinolytic examinations. By comparing the improvement ratio of these scores, therapeutic effect and clinical usefulness of FR-860 were evaluated into 5 types of excellently, moderately, slightly, unchanged （not useful） and aggravated （undesirable）. The efficacy of FR-860 was evaluated in 27 and 29 cases of the I and II groups, respectively, excluding 32 cases such as treated with other drugs simultaneously. No significant difference was observed in the case profile between the two groups. 6 cases died due to the underlying diseases or complications other than DIC. In bleeding symptoms, 45.5 and 48.0% cases of the each group showed more than moderately improvement. In organ failures and coagulation-fibrinolytic examinations, 31.6 and 66.7% cases showed markedly or moderately improvement in the I group, while they remained 14.3 and 51.7% in the II group, respectively. And then, FR-860 revealed useful in 66.7 and 58.6% cases of the each group. These results demonstrate that FR-860 is effective on DIC with a dose of 75 U/kg/ day.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "131296", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Oguma, Yutaka"}]}, {"nameIdentifiers": [{"nameIdentifier": "131297", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Sakuragawa, Nobuo"}]}, {"nameIdentifiers": [{"nameIdentifier": "131298", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Nakagawa, Masao"}]}, {"nameIdentifiers": [{"nameIdentifier": "131299", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Hasegawa, Hiroshi"}]}, {"nameIdentifiers": [{"nameIdentifier": "131300", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Maki, Masahiro"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "小熊, 豊"}], "nameIdentifiers": [{"nameIdentifier": "131291", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "桜川, 信男"}], "nameIdentifiers": [{"nameIdentifier": "131292", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "中川, 雅夫"}], "nameIdentifiers": [{"nameIdentifier": "131293", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "長谷川, 淳"}], "nameIdentifiers": [{"nameIdentifier": "131294", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "真木, 正博"}], "nameIdentifiers": [{"nameIdentifier": "131295", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "105(4)_272-278.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "105(4)_272-278.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/21475/files/105(4)_272-278.pdf"}, "version_id": "d1697297-3eec-4dcf-a4a2-ea1ea441942a"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "low molecular weight heparin (FR-860)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "DIC", "subitem_subject_scheme": "Other"}, {"subitem_subject": "A multicenter cooperative study", "subitem_subject_scheme": "Other"}, {"subitem_subject": "clinical effect", "subitem_subject_scheme": "Other"}, {"subitem_subject": "低分子ヘパリン", "subitem_subject_scheme": "Other"}, {"subitem_subject": "汎発性血管内血液凝固症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "多施設共同試験", "subitem_subject_scheme": "Other"}, {"subitem_subject": "臨床効果", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "低分子ヘパリン（FR-860）のDICに対する臨床効果", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "低分子ヘパリン（FR-860）のDICに対する臨床効果"}, {"subitem_title": "低分子ヘパリン（FR-860）のDICに対する臨床効果", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1187"], "permalink_uri": "http://hdl.handle.net/10191/38775", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-02-26"}, "publish_date": "2016-02-26", "publish_status": "0", "recid": "21475", "relation": {}, "relation_version_is_last": true, "title": ["低分子ヘパリン（FR-860）のDICに対する臨床効果"], "weko_shared_id": null}