WEKO3
アイテム
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低分子ヘパリン(FR-860)のDICに対する臨床効果
http://hdl.handle.net/10191/38775
http://hdl.handle.net/10191/38775efa16587-7e29-4793-8478-b1d3f24dd28d
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-02-26 | |||||
タイトル | ||||||
タイトル | 低分子ヘパリン(FR-860)のDICに対する臨床効果 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 低分子ヘパリン(FR-860)のDICに対する臨床効果 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | low molecular weight heparin (FR-860) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | DIC | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | A multicenter cooperative study | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | clinical effect | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 低分子ヘパリン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 汎発性血管内血液凝固症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 多施設共同試験 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 臨床効果 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Clinical Effect of Low Molecular Weight Heparin (FR-860) on DIC | |||||
著者 |
小熊, 豊
× 小熊, 豊× 桜川, 信男× 中川, 雅夫× 長谷川, 淳× 真木, 正博 |
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著者別名 | ||||||
識別子 | 131296 | |||||
識別子Scheme | WEKO | |||||
姓名 | Oguma, Yutaka | |||||
著者別名 | ||||||
識別子 | 131297 | |||||
識別子Scheme | WEKO | |||||
姓名 | Sakuragawa, Nobuo | |||||
著者別名 | ||||||
識別子 | 131298 | |||||
識別子Scheme | WEKO | |||||
姓名 | Nakagawa, Masao | |||||
著者別名 | ||||||
識別子 | 131299 | |||||
識別子Scheme | WEKO | |||||
姓名 | Hasegawa, Hiroshi | |||||
著者別名 | ||||||
識別子 | 131300 | |||||
識別子Scheme | WEKO | |||||
姓名 | Maki, Masahiro | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A study was intended to clarify the effectiveness of low molecular weight heparin (LMW Hp, FR-860;mean MW;4,400~5,600, KABI) on DIC. The research group was established among 49 nationwide institutes and 88 cases were challenged by FR-860 injection. The patients were divided into two groups and FR-860 was administered principally during 5 days with the doses of 75 U/kg/day in the I group (n=46) and 150 U/kg/day in the II group (n=42), respectively. Scoring points were defined according to the severity of bleeding symptoms, organ failures and abnormal coagulation-fibrinolytic examinations. By comparing the improvement ratio of these scores, therapeutic effect and clinical usefulness of FR-860 were evaluated into 5 types of excellently, moderately, slightly, unchanged (not useful) and aggravated (undesirable). The efficacy of FR-860 was evaluated in 27 and 29 cases of the I and II groups, respectively, excluding 32 cases such as treated with other drugs simultaneously. No significant difference was observed in the case profile between the two groups. 6 cases died due to the underlying diseases or complications other than DIC. In bleeding symptoms, 45.5 and 48.0% cases of the each group showed more than moderately improvement. In organ failures and coagulation-fibrinolytic examinations, 31.6 and 66.7% cases showed markedly or moderately improvement in the I group, while they remained 14.3 and 51.7% in the II group, respectively. And then, FR-860 revealed useful in 66.7 and 58.6% cases of the each group. These results demonstrate that FR-860 is effective on DIC with a dose of 75 U/kg/ day. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 105, 号 4, p. 272-278, 発行日 1991-04 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |