{"created":"2021-03-01T06:26:28.788835+00:00","id":21429,"links":{},"metadata":{"_buckets":{"deposit":"71a79ec6-4c68-427c-94c1-4432bfae8d46"},"_deposit":{"id":"21429","owners":[],"pid":{"revision_id":0,"type":"depid","value":"21429"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00021429","sets":["453:456","471:537:538:1186"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Immunoelectron Microscopic Study of Human Megakaryocytic Precursor Cells in Embryonal and Fetal Liver"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"325","bibliographicPageStart":"318","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Megakaryocytic series in human embryonal and fetal livers were studied by immunoelectron microscopy using anti Glycoprotein IIb/IIIa complex antibody. The livers were obtained from 25 embryos and fetuses from 38 days to 11 weeks of gestation. Megakaryocytic series from mature megakaryocyte （including platelet） to megakaryoblast were all positive for anti Glycoprotein IIb/IIIa. Some undifferentiated cells and macrophages revealed also positive reaction. The undifferentiated cells were regarded as progenitors of megakaryocytic cells. The megakaryocytic progenitor cells and megakaryoblast were subdivided into two subgroups （A-type and B-type）. The A-type cells were detected in the liver from 42 days of gestation. The cells were about 15μm in size, and had large nucleolus and finely dispersed chromatin. The B-type cells were detected in the liver from 50 days later, showing 7～10μm in diameter. The nucleus of the cells had obscure nucleoli and coarsely clumping chromatin. Morphologically the progenitors of A-type were quite different from B-type. These findings indicate that the ansestor of A-type megakaryocytic progenitor cells are different from those of B-type megakaryocytic progenitor cells. Consequently these data are consistent with the theory of our laboratory that presumptive hemopoietic stem cells are a series of cells consisting of four subtypes.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"131092","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Umezu, Hajime"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"梅津, 哉"}],"nameIdentifiers":[{"nameIdentifier":"131091","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"105(5)_318-325.pdf","filesize":[{"value":"7.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"105(5)_318-325.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/21429/files/105(5)_318-325.pdf"},"version_id":"cb7c4572-42dd-42a9-a644-f0ffccaef5cf"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"fetal hemopoiesis","subitem_subject_scheme":"Other"},{"subitem_subject":"megakaryocyte","subitem_subject_scheme":"Other"},{"subitem_subject":"immunoelectron microscopy","subitem_subject_scheme":"Other"},{"subitem_subject":"GP IIb/IIIa","subitem_subject_scheme":"Other"},{"subitem_subject":"胎児造血","subitem_subject_scheme":"Other"},{"subitem_subject":"巨核球","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫電顕","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ヒト胎児肝における巨核球前駆細胞の免疫電顕的検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒト胎児肝における巨核球前駆細胞の免疫電顕的検討"},{"subitem_title":"ヒト胎児肝における巨核球前駆細胞の免疫電顕的検討","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1186"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-02-26"},"publish_date":"2016-02-26","publish_status":"0","recid":"21429","relation_version_is_last":true,"title":["ヒト胎児肝における巨核球前駆細胞の免疫電顕的検討"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:51:58.236355+00:00"}