{"created":"2021-03-01T06:26:19.426418+00:00","id":21288,"links":{},"metadata":{"_buckets":{"deposit":"1ce5f458-a800-423f-91cf-5216af108f23"},"_deposit":{"id":"21288","owners":[],"pid":{"revision_id":0,"type":"depid","value":"21288"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00021288","sets":["453:456","471:537:538:1183"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Virological Study on Idiopathic Nephrotic Syndrome. Serum Level of 2'-5' Oligoadenylate Synthetase Activity and the Study of Virus Antigens in Oral Buccal Mucosa Smears"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"519","bibliographicPageStart":"509","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"To study the association of virus infections with the exacerbation of idiopathic nephrotic syndrome (INS), we have measured serum levels of 2'-5' oligoadenylate (2-5A) synthetase activities in patients with INS as a marker of virus infections. In adition, we have studied eight kinds of virus antigens (influenza A, B, parainfluenza 1～4, herpes simplex virus type 1, RSvirus) in oral buccal mucosa smears from patients with INS using immunofluorescent antibody technique. The results were as follows: 1) Serum levels of 2-5A in the INS active phase (onset or relapse) were significantly higher than those in the INS inactive phase (remission) and normal controls. 2) Because of high levels of serum 2-5A and clinical symptoms, we presumed that at least 44% of the exacerbations of INS were preceded by virus infections. 3) high levels of serum 2-5A decreased rapidly and returned to normal range within 1 week. 4) Virus antigens were detected in 24.5% of oral buccal mucosa smears from patients with INS active phase. Parainfluenza 3 was more frequent than other antigens.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"130350","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ogawa, Naoko"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小川, 直子"}],"nameIdentifiers":[{"nameIdentifier":"130349","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"105(8)_509-519.pdf","filesize":[{"value":"2.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"105(8)_509-519.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/21288/files/105(8)_509-519.pdf"},"version_id":"e37c4648-f506-4866-8e60-61d2b3e7687b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"idiopathic nephrotic syndrome","subitem_subject_scheme":"Other"},{"subitem_subject":"2'-5' oligoadenylate synthetase activity","subitem_subject_scheme":"Other"},{"subitem_subject":"virus infection","subitem_subject_scheme":"Other"},{"subitem_subject":"relapse","subitem_subject_scheme":"Other"},{"subitem_subject":"特発性ネフローゼ症候群","subitem_subject_scheme":"Other"},{"subitem_subject":"2'-5'オリゴアデニル酸合成酵素活性","subitem_subject_scheme":"Other"},{"subitem_subject":"ウイルス感染症","subitem_subject_scheme":"Other"},{"subitem_subject":"再発","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"特発性ネフローゼ症候群におけるウイルス学的研究 2'-5'オリゴアデニル酸合成酵素活性の動態と口腔内頬粘膜細胞塗抹標本のウイルス抗原検索について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"特発性ネフローゼ症候群におけるウイルス学的研究 2'-5'オリゴアデニル酸合成酵素活性の動態と口腔内頬粘膜細胞塗抹標本のウイルス抗原検索について"},{"subitem_title":"特発性ネフローゼ症候群におけるウイルス学的研究 2'-5'オリゴアデニル酸合成酵素活性の動態と口腔内頬粘膜細胞塗抹標本のウイルス抗原検索について","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1183"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-03-10"},"publish_date":"2016-03-10","publish_status":"0","recid":"21288","relation_version_is_last":true,"title":["特発性ネフローゼ症候群におけるウイルス学的研究 2'-5'オリゴアデニル酸合成酵素活性の動態と口腔内頬粘膜細胞塗抹標本のウイルス抗原検索について"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:51:51.907481+00:00"}