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Serum Level of 2\u0027-5\u0027 Oligoadenylate Synthetase Activity and the Study of Virus Antigens in Oral Buccal Mucosa Smears"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1991-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "8", "bibliographicPageEnd": "519", "bibliographicPageStart": "509", "bibliographicVolumeNumber": "105", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "To study the association of virus infections with the exacerbation of idiopathic nephrotic syndrome (INS), we have measured serum levels of 2\u0027-5\u0027 oligoadenylate (2-5A) synthetase activities in patients with INS as a marker of virus infections. In adition, we have studied eight kinds of virus antigens (influenza A, B, parainfluenza 1\uff5e4, herpes simplex virus type 1, RSvirus) in oral buccal mucosa smears from patients with INS using immunofluorescent antibody technique. The results were as follows: 1) Serum levels of 2-5A in the INS active phase (onset or relapse) were significantly higher than those in the INS inactive phase (remission) and normal controls. 2) Because of high levels of serum 2-5A and clinical symptoms, we presumed that at least 44% of the exacerbations of INS were preceded by virus infections. 3) high levels of serum 2-5A decreased rapidly and returned to normal range within 1 week. 4) Virus antigens were detected in 24.5% of oral buccal mucosa smears from patients with INS active phase. Parainfluenza 3 was more frequent than other antigens.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "130350", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ogawa, Naoko"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": 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