@article{oai:niigata-u.repo.nii.ac.jp:00021285, author = {大西, 昌之 and 伊藤, 粋子 and 真田, えい and 小田, 勇司 and 笠原, 紳 and 渡部, 透 and 高橋, 英明}, issue = {9}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Sep}, note = {We have studied antiplatelet therapy in patients with ischemic cerebrovascular disease for the prevention of ischemic stroke since 1978. Ninety-six patients, 10 with transient ischemic attack or reversible ischemic neurological deficit and 86 with cerebral infarction, were treated with low-dose aspirin and ticlopidine hydrochloride for the control of platelet aggregation. Ten patients had stroke recurrence at a rate of 2.7% per year. Five patients had bleeding: 3 involving alimentary tract hemorrhage, one had hemoptysis and one had a subdural hematoma. Two patients died of pneumonia. There were no significant differences regarding sex, age, or lesion sites. We conclude that low-dose aspirin and ticlopidine was effective in preventing ischemic cerebrovascular attacks.}, pages = {646--649}, title = {7) 当院における10年間のアスピリン・チクロピジン療法の成績(新潟血栓止血研究会10周年記念特別例会記録)}, volume = {105}, year = {1991} }