{"created":"2021-03-01T06:26:17.195298+00:00","id":21254,"links":{},"metadata":{"_buckets":{"deposit":"f6911908-d5b7-4003-b70c-7d48206f3cbb"},"_deposit":{"id":"21254","owners":[],"pid":{"revision_id":0,"type":"depid","value":"21254"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00021254","sets":["453:456","471:537:538:1180"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Study on the Health Risk Appraisal by Using Human Leukocyte Antigens (HLA)"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"759","bibliographicPageStart":"754","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In order to prevent the occurrence of diseases, the necessity for the total appraisal of risk factors has often been emphasized. As an appraisal procedure, the risk factors were isolated and their qualitative values evaluated in the population basis, then, the risk of the occurrence of disease was prognosticated at the individual levels. With these approaches, several risk factors, such as genetics, sex, age, nutrition and life style (physical exercise, smoking, drinking, etc. ) have been determined. Among them, the factors which can be altered to reduce risk are especially considered. In contrast, genetics in terms of disease susceptibility has not been taken into considerations for the risk appraisal, since it can't be altered to reduce risk. We found a high statistical association between gallbladder cancer and Major Histocompatibility Antigen (HLA), that is, HLA-DR4. Based on this epidemiological study on HLA, we tried to make clear the role of genetics on the occurrence of diseases. and to apply the HLA analysis to the health risk appraisal.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"130129","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Fujiguchi, Kensuke"}]},{"nameIdentifiers":[{"nameIdentifier":"130130","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Mano, Hiroshi"}]},{"nameIdentifiers":[{"nameIdentifier":"130131","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tsunoda, Masashi"}]},{"nameIdentifiers":[{"nameIdentifier":"130132","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakadaira, Hiroto"}]},{"nameIdentifiers":[{"nameIdentifier":"130133","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Endoh, Kazuo"}]},{"nameIdentifiers":[{"nameIdentifier":"130134","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yamamoto, Masaharu"}]},{"nameIdentifiers":[{"nameIdentifier":"130135","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Watanabe, Gen-ichi"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藤口, 憲輔"}],"nameIdentifiers":[{"nameIdentifier":"130122","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"真野, 裕"}],"nameIdentifiers":[{"nameIdentifier":"130123","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"角田, 正史"}],"nameIdentifiers":[{"nameIdentifier":"130124","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中平, 浩人"}],"nameIdentifiers":[{"nameIdentifier":"130125","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"遠藤, 和男"}],"nameIdentifiers":[{"nameIdentifier":"130126","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山本, 正治"}],"nameIdentifiers":[{"nameIdentifier":"130127","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡辺, 厳一"}],"nameIdentifiers":[{"nameIdentifier":"130128","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"105(11)_754-759.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"105(11)_754-759.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/21254/files/105(11)_754-759.pdf"},"version_id":"ee7ea2c1-0aa2-498f-a1cc-d39b7f7fcdc4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HLA","subitem_subject_scheme":"Other"},{"subitem_subject":"health risk appraisal","subitem_subject_scheme":"Other"},{"subitem_subject":"主要組織適合抗原","subitem_subject_scheme":"Other"},{"subitem_subject":"健康危険度評価","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"HLAを用いた健康危険度評価法に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"HLAを用いた健康危険度評価法に関する研究"},{"subitem_title":"HLAを用いた健康危険度評価法に関する研究","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1180"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-03-11"},"publish_date":"2016-03-11","publish_status":"0","recid":"21254","relation_version_is_last":true,"title":["HLAを用いた健康危険度評価法に関する研究"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:51:45.860366+00:00"}