@article{oai:niigata-u.repo.nii.ac.jp:00021092, author = {小幡, 明博}, issue = {3}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Mar}, note = {In order to clarify risk factors of coronary heart disease in Japan, a comparative study was conducted on young adults, in which the westernized lifestyle has been well settled and in whom incidental coronary atherosclerosis may occur in the near future. Forty-five consecutive patients under 40 years of age with coronary heart disease were investigated. All of them were male. As age-matched neighboring controls, 90 healthy post-office workers were employed. In the present study, smoking, diabetes mellitus, low HDL-cholesterol and hypertension emerged as significant risk factors independently related to coronary heart disease in the young Japanese generation. American and European trials have indicated that age, blood pressure, serum cholesterol, smoking, diabetes mellitus and obesity are the main independent factors. Moreover, low HDL-cholesterol has also recently been noticed as an important factor. Preventive studies for coronary heart disease which have been undertaken in American and European countries, informs us that lowering of serum cholesterol, hypotensive therapy and cessation of smoking are very effective. Through the present analysis, how to manage smoking, serum cholesterol, hypertension and diabetes mellitus have become the main tasks in order to prevent coronary heart disease in Japan.}, pages = {180--187}, title = {6) 虚血性心疾患の予防(シンポジウム 虚血心疾患の治療と最近の話題, 第470回新潟医学会)}, volume = {106}, year = {1992} }