@article{oai:niigata-u.repo.nii.ac.jp:00021058,
 author = {太田, 一寿},
 issue = {4},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Apr},
 note = {In a study undertaken to elucidate the role of the fatty acid binding protein (FABP) in the colon and rectum, the intensity of FABP immunostaining (PAP method) with anti-FABP antibodies was studied in 82 patients with advanced colorectal cancer. In 80 of them, the findings were compared with the flow cytometric DNA ploidy pattern, which is useful for evaluating the biological malignant potential in colorectal cancer. The intensity of FABP immunostaining varied significantly with the histologic type, node metastasis, and histologic stage of colorectal cancer, and showed a significant difference with the flow cytometric DNA ploidy pattern, while it did not significantly differ with sex, average age, the site of involvement, gross type, depth of invasion or vessel invasion. The cumulative postoperative survival rate was significantly higher in the patients with high intensity FABP immunostaining than in those with low intensive staining both in the entire series and in a series of 60 patients with curative resection (p＜0.001). These results suggest that the intensity of FABP immunostaining might indicate a prognostic role in patients with advanced colorectal cancer.},
 pages = {310--321},
 title = {進行大腸癌における脂肪酸結合蛋白の免疫組織学的検討 : 臨床病理学的所見, DNA ploidy patternとの比較},
 volume = {106},
 year = {1992}
}