@article{oai:niigata-u.repo.nii.ac.jp:00021057, author = {佐藤, 勇}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {An existing ultrasound Doppler method for measuring cardiac output has been improved and refined. In the present study, the accuracy of Doppler estimation of cardiac output in various types of stenosis was experimentally and clinically evaluated. The experimental model was designed to create pulsatile flow through a stenosis model. Six different stenosis model types, were used, including three orifice-like stenosis and three truncated cones with heights of 10mm distal to the stenosis. The orifices in their stenosis were 3, 4 and 5mm respectively. The circulation medium was glycerin solution containing Sephadex with three types of viscosity (1.21mPa.s, 3.45mPa.s, 5.35mPa.s). In each stenosis model, flow profile images were recorded using continuous wave Doppler and stroke volume was calculated by measuring the area integrating the velocity signal curve (time averaged mean) and the stenotic area. Stroke volume measured by this method was compared with that measured by electromagnetic flowmeter. Thirteen patients, including seven with aortic and pulmonary valvular stenosis, four with infundibular, and two with supravalvular aortic or pulmonary stenosis were observed. The cardiac output was obtained at the time of catheterization using thermodilution method in all patients. At the time of catheterization or near the catheterization, the maximum velocity of the stenotic lesion was recorded by continuous Doppler echocardiography and the diameter of the stenotic lesion was measured by color flow imaging. Using this Doppler method, stroke volume was calculated and compared with that of thermo-dilution method. Experimental results: In all type of stenosis, and in two kinds of viscosity liquid (3.45mPa.s, 5.35mPa.s), the regression equation between the stroke volume calculated by the Doppler method (Y) and that of measured by electromagnetic flowmeter (X) was Y=1.501X-0.086 (r=0.946, p<0.0001) regardless of the orifice size and post stenotic form. Using abnormal low viscosity liquid (1.21mPa.s), the regression equation was Y=4.402X-0.358 (r=0.961, p<0.0001). Stroke volume measured by Doppler method was more overestimated. Clinical results: the regression equation between the stroke volume calculated by the Doppler method (Y) and that of measured by thermo-dilution method (X) was Y= 1.251X-11.732 (r=0.85, p<0.005). The evaluation of stenotic area was most important factor for estimating the stroke volume using Doppler method.}, pages = {301--309}, title = {超音波ドプラ法を用いた狭窄部位における心拍出量計測法の試み : 実験的および臨床的検討}, volume = {106}, year = {1992} }