@article{oai:niigata-u.repo.nii.ac.jp:00021053, author = {山崎, ユウ子}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {Blood pressure and heart rate of streptozotocin diabetic rats (60mg/kg) were compared with those of age-matched controls during 1) supine and prone tilt, 2) carotid artery occlusion and 3) cervical vagus or sympathetic nerve stimulation under urethane anesthesia (1g/kg). Blood pressure and heart rate of diabetic rats were lower than those of normal rats. Heart rate variation (R-R Interval Variation) of the diabetic rats were larger than that of normal. Blood pressure fall in supine and prone tilt was significantly larger in diabetic than in normal control rats. Heart rate rise (compensatory tachycardia) and the recovery from the blood pressure fall during the tilt were seen on prone tilt of normal rats but those were hardly seen in diabetic rats. Reflex rise of blood pressure during carotid artery occlusion was lower in diabetic than in normal rats. These changes may be derived from the diabetic autonomic neuropathy and diabetic changes of effector organs, the cardiovascular system. Autonomic reflex arc, afferent and efferent limbs and central relay neurons, may be disordered.}, pages = {257--266}, title = {ウレタン麻酔下でのストレプトゾトシン糖尿病ラットにおける血圧と心拍数の変化}, volume = {106}, year = {1992} }