@article{oai:niigata-u.repo.nii.ac.jp:00021051, author = {小田野, 行男}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {Single photon emission computed tomography (SPECT) using N-isopropyl-p-[^<123>I] iodoamphetamine (IMP) studies were performed on 17 patients (23-77 yrs) with cerebrovascular diseases and 10 age-matched normal controls. Regional cerebral blood flow (rCBF) was quantitatively measured by a microsphere model, and a relationship between rCBF in ischemic lesions and the redistribution phenomenon on delayed SPECT image was analyzed. Supratentorial mean CBF and a gray-to-white matter ratio of normal subjects were 52.7±5.0ml/100g/min and 2.34, respectively. Low activity areas of ischemic lesions on early IMP SPECT were classified into two abnormal zones, an infarct area and a peri-infarct area. These regions were characterized by rCBF averaging 9~20ml/100g/min, and 25~40ml/100g/min, respectively. The redistribution, which was hardly observed in the infarct area, was markedly enhanced in the peri-infarct area. The data indicates that the redistribution depends on maintenance of a minimal blood flow that would sustain cellular function.}, pages = {243--247}, title = {N-Isopropyl-p-[^<123>I]Iodoamphetamine(IMP)SPECTにおけるDelayed Fill-in Phenomenon(いわゆる再分布現象)の意義}, volume = {106}, year = {1992} }