@article{oai:niigata-u.repo.nii.ac.jp:00020977,
 author = {宮島, 静一},
 issue = {5},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {May},
 note = {Ventricular tachyarrhythmias are prevalent in patients with cardiomyopathy and are associated with an increased risk of sudden death. In this study, we elucidated the role of electrophysiologic study in the evaluation and management of patients with cardiomyopathy and ventricular tachycardia(VT). Our findings are as follow : (1) Of 11 patients with dilated cardiomyopathy presenting with sustained VT, VT was induced and terminated with programmed ventricular stimulation in 8 patients. In 10 patients, VT was drug-resistant. The sites of origin of VT were present at both ventricles. Since most patients without effective antiarrhythmic tharapy died (8 of 11), aggressive therapy is mandatory in these patients. (2) One patient with alcoholic cardiomyopathy had multiple form of VT. VT was induced and terminated with programmed stimulation. Flecainide was effective in preventing VT. (3) In patients with hypertrophic cardiomyopathy, VT was induced in 3 of 4 patients with sustained VT or VF, in 6 of 16 patients with other arrhythmias. Verapamil or mexiletine was effective in 7 of 9 patients. Patients with effective antiarrhythmic dugs have not suffered from sudden death. We conclude that drug-resistant VT should be managed aggressively in patients with cardiomyopathy.},
 pages = {436--453},
 title = {心室頻拍を合併した心筋症の電気生理学的評価と治療の意義},
 volume = {106},
 year = {1992}
}