@article{oai:niigata-u.repo.nii.ac.jp:00020975, author = {須田, 昌司}, issue = {5}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {May}, note = {Systolic and diastolic blood pressures, erythrocyte sodium (Na) and plasma Na concentrations, plasma Na/erythrocyte Na ratio, plasma magnesium (Mg^<2+>) and ionized calcium (Ca^<2+>) concentrations and plasma Ca^<2+>/Mg^<2+> ratio were measured according to hours after birth during first week in 21 healthy term infants. Erythrocyte Na concentrations gradually increased to plateau levels 48 hours after birth. Plasma Na/erythrocyte Na ratio decreased 48 hours after birth since erythrocyte Na increased. Both systolic and diastolic blood pressures began to increase 72 hours after birth in contrast with plasma Na/erythrocyte Na ratio. Plasma Ca^<2+> concentrations and Ca^<2+>/Mg^<2+> ratio decreased at the bottom 24 hours after birth, when blood pressures were low. The rate of variance of blood pressure [(BP at each hour-BP at 3 hours after birth)/BP at 3 hours after birth] was inversely correlated with that of plasma Na/erythrocyte Na ratio (systolic BP : n=126, P<0.001 ; diastolic BP : n=126, P<0.001), and erythrocyte Na concentration was correlated with plasma Ca^<2+> concentration (P<0.001) and was inversely correlated with plasma Mg^<2+> concentration and potassium concentration (P<0.001). The sodium efflux rate constant at 1st day was more than that at 5th day after birth when both systolic blood pressure and diastolic blood pressure were raised. These findings suggest that the Na transport in cell membrane may have some significant roles in regulating blood pressure in early neonatal period, and that the extracellular Ca^<2+>, Mg^<2+> and K may have influence on the Na transport in cell membrane.}, pages = {413--423}, title = {小児の血圧と電解質に関する研究 第2編 新生児早期の血圧と赤血球膜ナトリウム輸送の関連}, volume = {106}, year = {1992} }