@article{oai:niigata-u.repo.nii.ac.jp:00020939, author = {桑原, 武夫}, issue = {6}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jun}, note = {We have studied the water permeability through membranes, the function of the Na pump, and glucose metabolism of erythrocytes of patients with myotonic muscular dystrophy (MyD) using ^1H-, ^<23>Na, and ^<13>C-magnetic resonance spectroscopy (MRS). A significant decrease in water permeability was recognized in the MyD erythrocyte membrane, and impared Na pumping was suspected to be correlated with the former biochemical abnormalities in band III protein. of MyD erythrocyte membrane. Significant accelation of glycolysis in erythrocyte for the first 160 minutes was also recognized in MyD however, the production of lactate showed no difference between MyD and controls. The increased glucose uptake in MyD may be compensatory to the diminished pumping mechanism, but further information, such as inorganic phosphate permeability and the activity of the rate-limiting enzyme of erythrocyte glycolysis is needed.}, pages = {563--572}, title = {筋緊張性ジストロフィー症患者赤血球の磁気共鳴法による研究}, volume = {106}, year = {1992} }