ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "f0d7d6ac-c3e6-4307-a93c-b5812158902a"}, "_deposit": {"id": "20936", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20936"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00020936", "sets": ["456", "1173"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Dynamic Analysis of the Peripheral Blood Lymphocyte Subsets Following the Intensive Treatment for Patients with Malignant Brain Tumors"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "542", "bibliographicPageStart": "536", "bibliographicVolumeNumber": "106", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "To investigate the influence of the intensive treatment for malignant brain tumors on the cellular immunological functions, the dynamic changes of the peripheral blood lymphocytes subsets during the therapy was studied. PBLs collected from 21 maligmant brain tumor patients were examined by two-color flow cytometric analysis using Leu series monoclonal antibodies. Patients were divided into three groups according to the treatment regimen; (R) brain irradiation only, n=4; (A) (R)+1-(4-amino-2-methyl-5-pyrimidyl) methyl-3-nitrosourea hydrochloride, n=7; and (I) (A)+OK 432 or interferon-β, n=10. Results presented herein are summarized as below; 1) T(Leu 4+12-) cells have increased in all groups and B (Leu 4-12+) cells have decreased significantly (p<0.05) in groups R and A. B cells have also decreased in group I. 2) All groups showed an increase in activated T (Leu 4+HLADR+) cells before the treatment. Moreover, in groups R and A, these activated T cells have increased significantly (p<0.05) during the therapy. Activated T cells have also increased in group I. 3) CD4/CD8 ratios have decreased in groups R and A. In group I, however, it has remained nearly constant during the therapy. 4) Cytotoxic T (Leu2a+15-) cells have increased almost in parallel with activated T cells. So, the major component of the increased aetivated Tcells were thought to be the cytotoxic Tcells. 5) Strong NK(Leu 7-11+) cells have increased in all groups and moderate NK (Leu7+11+) cells have increased in groups R and A. Our data may suggest that the immunological states of the patients, especially those treated with biological response modifiers, get to be favorable state from the view point of the antitumor immunity during the intensive treatment.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "128562", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Mori, Hiroshi"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "森, 宏"}], "nameIdentifiers": [{"nameIdentifier": "128561", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "106(06)_536-542.pdf", "filesize": [{"value": "1.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1500000.0, "url": {"label": "106(06)_536-542.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/20936/files/106(06)_536-542.pdf"}, "version_id": "474e55b7-3529-47a3-9f25-300decccc902"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "malignant brain tumor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "treatment", "subitem_subject_scheme": "Other"}, {"subitem_subject": "lymphocyte subsets", "subitem_subject_scheme": "Other"}, {"subitem_subject": "biological response modifier", "subitem_subject_scheme": "Other"}, {"subitem_subject": "flow cytometry", "subitem_subject_scheme": "Other"}, {"subitem_subject": "悪性脳腫瘍", "subitem_subject_scheme": "Other"}, {"subitem_subject": "治療", "subitem_subject_scheme": "Other"}, {"subitem_subject": "リンパ球サブセット", "subitem_subject_scheme": "Other"}, {"subitem_subject": "バイオロジカルレスポンスモディファイアー", "subitem_subject_scheme": "Other"}, {"subitem_subject": "フローサイトメーター", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "悪性脳腫瘍患者末梢血リンパ球サブセット動態におよぼす集学的治療の効果", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "悪性脳腫瘍患者末梢血リンパ球サブセット動態におよぼす集学的治療の効果"}, {"subitem_title": "悪性脳腫瘍患者末梢血リンパ球サブセット動態におよぼす集学的治療の効果", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1173"], "permalink_uri": "http://hdl.handle.net/10191/39772", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-03-15"}, "publish_date": "2016-03-15", "publish_status": "0", "recid": "20936", "relation": {}, "relation_version_is_last": true, "title": ["悪性脳腫瘍患者末梢血リンパ球サブセット動態におよぼす集学的治療の効果"], "weko_shared_id": null}
  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第106巻第6号

悪性脳腫瘍患者末梢血リンパ球サブセット動態におよぼす集学的治療の効果

http://hdl.handle.net/10191/39772
http://hdl.handle.net/10191/39772
bc0bdbb7-d28e-4073-8773-dabe54d15e20
名前 / ファイル ライセンス アクション
106(06)_536-542.pdf 106(06)_536-542.pdf (1.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-03-15
タイトル
タイトル 悪性脳腫瘍患者末梢血リンパ球サブセット動態におよぼす集学的治療の効果
タイトル
言語 en
タイトル 悪性脳腫瘍患者末梢血リンパ球サブセット動態におよぼす集学的治療の効果
言語
言語 jpn
キーワード
主題Scheme Other
主題 malignant brain tumor
キーワード
主題Scheme Other
主題 treatment
キーワード
主題Scheme Other
主題 lymphocyte subsets
キーワード
主題Scheme Other
主題 biological response modifier
キーワード
主題Scheme Other
主題 flow cytometry
キーワード
主題Scheme Other
主題 悪性脳腫瘍
キーワード
主題Scheme Other
主題 治療
キーワード
主題Scheme Other
主題 リンパ球サブセット
キーワード
主題Scheme Other
主題 バイオロジカルレスポンスモディファイアー
キーワード
主題Scheme Other
主題 フローサイトメーター
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Dynamic Analysis of the Peripheral Blood Lymphocyte Subsets Following the Intensive Treatment for Patients with Malignant Brain Tumors
著者 森, 宏

× 森, 宏

WEKO 128561

森, 宏

Search repository
著者別名
識別子 128562
識別子Scheme WEKO
姓名 Mori, Hiroshi
抄録
内容記述タイプ Abstract
内容記述 To investigate the influence of the intensive treatment for malignant brain tumors on the cellular immunological functions, the dynamic changes of the peripheral blood lymphocytes subsets during the therapy was studied. PBLs collected from 21 maligmant brain tumor patients were examined by two-color flow cytometric analysis using Leu series monoclonal antibodies. Patients were divided into three groups according to the treatment regimen; (R) brain irradiation only, n=4; (A) (R)+1-(4-amino-2-methyl-5-pyrimidyl) methyl-3-nitrosourea hydrochloride, n=7; and (I) (A)+OK 432 or interferon-β, n=10. Results presented herein are summarized as below; 1) T(Leu 4+12-) cells have increased in all groups and B (Leu 4-12+) cells have decreased significantly (p<0.05) in groups R and A. B cells have also decreased in group I. 2) All groups showed an increase in activated T (Leu 4+HLADR+) cells before the treatment. Moreover, in groups R and A, these activated T cells have increased significantly (p<0.05) during the therapy. Activated T cells have also increased in group I. 3) CD4/CD8 ratios have decreased in groups R and A. In group I, however, it has remained nearly constant during the therapy. 4) Cytotoxic T (Leu2a+15-) cells have increased almost in parallel with activated T cells. So, the major component of the increased aetivated Tcells were thought to be the cytotoxic Tcells. 5) Strong NK(Leu 7-11+) cells have increased in all groups and moderate NK (Leu7+11+) cells have increased in groups R and A. Our data may suggest that the immunological states of the patients, especially those treated with biological response modifiers, get to be favorable state from the view point of the antitumor immunity during the intensive treatment.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 106, 号 6, p. 536-542, 発行日 1992-06
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 13:53:20.999446
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3